J
Jean-Pierre Kraehenbuhl
Researcher at University of Lausanne
Publications - 142
Citations - 12457
Jean-Pierre Kraehenbuhl is an academic researcher from University of Lausanne. The author has contributed to research in topics: Antigen & Immune system. The author has an hindex of 59, co-authored 142 publications receiving 12176 citations. Previous affiliations of Jean-Pierre Kraehenbuhl include Ludwig Institute for Cancer Research & ISREC.
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Conversion by Peyer's Patch Lymphocytes of Human Enterocytes into M Cells that Transport Bacteria
TL;DR: In this paper, a cultured system that reproduces the main characteristics of FAE and M cells was established by cultivation of Peyer's patches (PPs) with the differentiated human intestinal cell line Caco-2.
Journal Article
Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria (see comments).
TL;DR: A cultured system that reproduces the main characteristics of FAE and M cells was established by cultivation of PP lymphocytes with the differentiated human intestinal cell line Caco-2, inducing reorganization of the brush border and a temperature-dependent transport of particles and Vibrio cholerae.
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Collaboration of epithelial cells with organized mucosal lymphoid tissues
TL;DR: Determination of the earliest cellular interactions that occur in and under the follicle-associated epithelium could greatly facilitate the design of effective mucosal vaccines in the future.
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Epithelial m cells : gateways for mucosal infection and immunization
TL;DR: Future studies on the interactions of micoorganisms with this highly specialized epithelial cell will enhance the understanding of microbial pathogenesis and will lead to more effective strategies for targeting of vaccines and live microbial vaccine vectors to the mucosal immune system.
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Antigen sampling across epithelial barriers and induction of mucosal immune responses
TL;DR: The features of M cells that determine antigen and pathogen adherence and transport into mucosal lymphoid tissues are reviewed.