Jean-Pierre Majoral

TL;DR: Dendrimer ABP, by doubling up against inflammation and bone erosion, might be more effective at treating RA than existing antibody- and small-molecule–based biologic drugs.

TL;DR: In this article, the development of a macromolecular chemistry within the cavities of dendrimers is illustrated by two examples of construction of six Dendrimer units within the cascade structure of a main Dender, and the preparation of these multidendritic systems involves the regioselective modification of the framework of the central Dender to create internal reactive centers.

TL;DR: The contribution of dendrimers to the field of nanomedicine is discussed in this article, focusing on the extraordinary possibilities offered by their multivalent and defined structure, as well as the underlying concepts that make Dendrimeric systems so attractive.

TL;DR: New series of phosphorus-containing dendrimers, having one quaternary ammonium salt as core and carboxylic acid terminal groups have been synthesized from generation 0 to generation 2, which react with the neutral form of carteolol to afford ion pair (saline) species.