J
Jeffrey A. Durocher
Publications - 2
Citations - 819
Jeffrey A. Durocher is an academic researcher. The author has contributed to research in topics: Gel electrophoresis & Cancer. The author has an hindex of 2, co-authored 2 publications receiving 744 citations.
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Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors
Michael L. Nickerson,Erich Jaeger,Yangu Shi,Jeffrey A. Durocher,Sunil Mahurkar,David Zaridze,Vsevolod Matveev,Vladimir Janout,H. Kollarova,Vladimir Bencko,Marie Navratilova,Neonilia Szeszenia-Dabrowska,Dana Mates,Anush Mukeria,Ivana Holcatova,Laura S. Schmidt,Jorge R. Toro,Sara Karami,Rayjean J. Hung,Rayjean J. Hung,Gary F. Gerard,W. Marston Linehan,Maria J. Merino,Berton Zbar,Paolo Boffetta,Paul Brennan,Nathaniel Rothman,Wong Ho Chow,Frederic M. Waldman,Lee E. Moore +29 more
TL;DR: Analysis of patient and tumor characteristics revealed that certain mutation subtypes were significantly associated with Fuhrman nuclear grade, metastasis, node positivity, and self-reported family history of RCC, indicating that VHL molecular subtypes can provide a sensitive marker of tumor heterogeneity among histologically similar ccRCC cases for etiologic, prognostic, and translational studies.
Journal ArticleDOI
Mutation detection using Surveyor nuclease.
Peter Qiu,Harini Shandilya,James M. D'Alessio,Kevin C. O’Connor,Jeffrey A. Durocher,Gary F. Gerard +5 more
TL;DR: The technology is highly sensitive, detecting rare mutants present at as low as 1 in 32 copies and can be performed in less than a day and is suitable for automated and high-throughput procedures.