Jeffrey K Aronson

TL;DR: There was a statistically significant increase in the [3H]-ouabain binding capacity of the lymphocyte membranes (reflecting the number of Na+, K+-ATPase molecules) after 14 days of lithium administration in vivo, which suggests that a failure to increase pump numbers after similar exposure to lithium in vivo in patients with manic-depressive psychosis is a primary abnormality associated with the disease.

TL;DR: Allopurinol and nicotinamide are unlikely to be of value as tryptophan pyrrolase inhibitors in vivo and therefore would not increase the therapeutic effect of L-tryptophan when it is given to treat depressive illness.

TL;DR: As arguments between doctors and advocates of alternative medicine continue, Jeff Aronson describes how the secret ingredients of patent medicines were uncovered a century ago.

TL;DR: The BM1A EB-virus transformed human lymphocyte cell line contains approximately 950,000 Na+/K(+)-ATPase sites per cell, and the finding that monensin is capable of inducing both the short- and long-term changes associated with a low external concentration of potassium is supported.