J
Jeffrey M. Marinshaw
Researcher at Washington University in St. Louis
Publications - 4
Citations - 719
Jeffrey M. Marinshaw is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Intestinal epithelium & Intestinal mucosa. The author has an hindex of 3, co-authored 4 publications receiving 579 citations.
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Journal ArticleDOI
Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays
Kelli L. VanDussen,Jeffrey M. Marinshaw,Nurmohammad Shaikh,Hiroyuki Miyoshi,Clara Moon,Phillip I. Tarr,Matthew A. Ciorba,Thaddeus S. Stappenbeck +7 more
TL;DR: A large panel of human gastrointestinal epithelial cell lines from patient biopsies taken during routine upper and lower endoscopy procedures are created to facilitate the study of interindividual, functional studies of human intestinal epithelial cells, including host–microbial interactions.
Journal ArticleDOI
Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner
Matthew A. Ciorba,Terrence E. Riehl,M. Suprada Rao,Clara Moon,Xueping Ee,Gerardo M. Nava,Monica R. Walker,Jeffrey M. Marinshaw,Thaddeus S. Stappenbeck,William F. Stenson +9 more
TL;DR: LGG or its CM reduce radiation-induced epithelial injury and improve crypt survival and a TLR-2/MyD88 signalling mechanism leading to repositioning of constitutive COX-2-expressing mesenchymal stem cells to the crypt base is invoked.
Journal ArticleDOI
IDO1 Metabolites Activate β-catenin Signaling to Promote Cancer Cell Proliferation and Colon Tumorigenesis in Mice
Ameet I. Thaker,M. Suprada Rao,Kumar S. Bishnupuri,Thomas A. Kerr,Lynne Foster,Jeffrey M. Marinshaw,Rodney D. Newberry,William F. Stenson,Matthew A. Ciorba +8 more
TL;DR: IDO1, which catabolizes tryptophan, promotes colitis-associated tumorigenesis in mice, independent of its ability to limit T-cell-mediated immune surveillance, indicates its potential as a therapeutic target.