Jenifer Juranek

TL;DR: The relative carnitine deficiency in these patients, accompanied by slight elevations in lactate and significant Elevations in alanine and ammonia levels, is suggestive of mild mitochondrial dysfunction.

TL;DR: Two autistic children with a chromosome 15q11‐q13 inverted duplication have muscle mitochondrial enzyme assays that showed a pronounced mitochondrial hyperproliferation and a partial respiratory chain block most parsimoniously placed at the level of complex III, suggesting candidate gene loci for autism within the critical region may affect pathways influencing mitochondrial function.

TL;DR: A significant brain-behavior relationship between amygdala volume and anxious/depressed scores on the Child Behavior Checklist in an autistic cohort is identified, supporting reported evidence for a neurobiologic relationship between symptoms of anxiety and depression with amygdala structure and function.

TL;DR: Given equally complex ocular motor, motor, and cognitive phenotypes consisting of relative strengths and weaknesses that seem to align with altered structural development, studies of SBM provide new insights to the authors' current understanding of brain structure-function associations.

TL;DR: Lower motor cortex activity at baseline predicted greater behavioral gains after therapy, even after controlling for a number of clinical assessments, and boosts in cortical activity that paralleled behavioral gains suggest that in some patients, low baseline cortical activity represents underuse of surviving cortical resources.