J
Jennifer Diedler
Researcher at University of Tübingen
Publications - 70
Citations - 2455
Jennifer Diedler is an academic researcher from University of Tübingen. The author has contributed to research in topics: Stroke & Intracerebral hemorrhage. The author has an hindex of 26, co-authored 70 publications receiving 2045 citations. Previous affiliations of Jennifer Diedler include Heidelberg University & University of Cambridge.
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Journal ArticleDOI
Critical thresholds for cerebrovascular reactivity after traumatic brain injury.
Enrico Sorrentino,Jennifer Diedler,Magdalena Kasprowicz,Karol P. Budohoski,Christina Haubrich,Peter Smielewski,Joanne G. Outtrim,Anne E. Manktelow,Peter J. Hutchinson,John D. Pickard,David K. Menon,Marek Czosnyka +11 more
TL;DR: The prognostic role of PRx is confirmed but with a lower threshold of 0.05 for favorable outcome than for survival (0.25) and the lower value in elderly and in females suggests increased vulnerability to intracranial hypertension in these groups.
Journal ArticleDOI
Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury.
Daniel N. Hertle,Jens P. Dreier,Johannes Woitzik,Jed A. Hartings,Ross Bullock,David O. Okonkwo,Lori Shutter,Steven Vidgeon,Anthony J. Strong,Christina M. Kowoll,Christian Dohmen,Jennifer Diedler,Roland Veltkamp,Thomas Bruckner,Andreas Unterberg,Oliver W. Sakowitz +15 more
TL;DR: The findings suggest that ketamine-or another N-methyl-d-aspartate receptor antagonist-may represent a viable treatment for patients at risk for spreading depolarizations and this hypothesis will be tested in a prospective study.
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Safety of Intravenous Thrombolysis for Acute Ischemic Stroke in Patients Receiving Antiplatelet Therapy at Stroke Onset
Jennifer Diedler,Niaz Ahmed,Marek Sykora,Maarten Uyttenboogaart,Karsten Overgaard,Gert-Jan Luijckx,Lauri Soinne,Gary A. Ford,Kennedy R. Lees,Nils Wahlgren,Peter A. Ringleb +10 more
TL;DR: The absolute excess of SICH of 1.4% (2.1%) in the pooled AP group is small compared with the benefit of thrombolysis seen in randomized trials, and although caution is warranted in patients receiving the combination of ASA and clopidogrel, AP treatment should not be considered a contraindication to thrombosis.
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Impaired baroreflex sensitivity predicts outcome of acute intracerebral hemorrhage.
TL;DR: It is found that BRS was decreased in patients with acute intracerebral hemorrhage and correlated with increased beat-to-beat blood pressure variability, which may represent a new therapeutic target in acute stroke.
Journal ArticleDOI
Baroreflex: a new therapeutic target in human stroke?
TL;DR: In this article, the role of baroreflex impairment in acute stroke and its possible pathophysiological and therapeutic relevance was discussed, suggesting that modifying of autonomic functions may have important therapeutic implications in acute ischemic as well as in hemorrhagic stroke.