Jennifer J Kurinczuk

TL;DR: Infants conceived with use of intracytoplasmic sperm injection or in vitro fertilization have twice as high a risk of a major birth defect as naturally conceived infants.

TL;DR: The causes of newborn encephalopathy are heterogeneous and many of the causal pathways start before birth, including maternal thyroid disease, severe pre-eclampsia, and infertility treatment.

TL;DR: Pooled results from all suitable published studies suggest that children born following ART are at increased risk of birth defects compared with spontaneous conceptions.

TL;DR: A welcome decrease in the overall rate of maternal death across the United Kingdom is shown, and a compelling message for the future has to be the importance of continuing the programme of vaccination against influenza in pregnancy in the UK and Ireland, working to maximise uptake and hence to ensure the authors prevent future influenza-related maternal deaths.

TL;DR: The results question the view that most risk factors for newborn encephalopathy lie in the intrapartum period and suggest that antepartum hypoxia alone accounts for only a small proportion of newborn enphalopathy.