J
Jennifer Lagendijk
Researcher at University of Pretoria
Publications - 6
Citations - 295
Jennifer Lagendijk is an academic researcher from University of Pretoria. The author has contributed to research in topics: HMG-CoA reductase & Whole blood. The author has an hindex of 6, co-authored 6 publications receiving 291 citations.
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Measurement of the ratio between the reduced and oxidized forms of coenzyme Q10 in human plasma as a possible marker of oxidative stress.
TL;DR: The results indicate that CoQ10H2 is unstable in whole blood, plasma, and isopropanol extracts; subsequently the CoQ 10H2/CoQ10 ratio changes considerably soon after a blood sample has been obtained, and this indicator is independent from plasma total cholesterol concentrations, implying that groups who differ with respect to cholesterol levels may be compared directly.
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The effect of Simvastatin on the plasma antioxidant concentrations in patients with hypercholesterolaemia
Johanna A. Human,Johan B. Ubbink,Johann J. Jerling,Rhena Delport,W. J. Hayward Vermaak,H H Vorster,Jennifer Lagendijk,Hendrik C. Potgieter +7 more
TL;DR: The results suggest that the significant decline in circulating alpha-tocopherol and coenzyme Q10 concentrations was mainly a function of the decrease in serum total cholesterol concentrations, indicating that LDL from the former group may be more vulnerable to free radical-mediated damage and lipid peroxidation.
Journal Article
Ubiquinol/ubiquinone ratio as marker of oxidative stress in coronary artery disease.
TL;DR: It is indicated that circulating lipoproteins of CAD patients are more exposed to, or are more susceptible to, free radical reactions compared with apparently healthy controls, and that an altered ubiquinol/ubiquinone ratio is the first sign of lipoprotein exposure to oxidative stress.
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The determination of allantoin, a possible indicator of oxidant status, in human plasma
TL;DR: Clinical studies can now be performed to evaluate allantoin as a possible indicator of free radical damage in vivo, and a preliminary reference range is reported.
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Simple high-performance liquid chromatographic method to verify the direct barbituric acid assay for urinary cotinine
TL;DR: It is concluded that the direct barbituric acid assay is a very reliable indicator of smoking status, provided that urine blank samples are prepared to correct for background absorbance.