Jennifer M. K. Cheong

TL;DR: An overview of the evidence of the effect of purified soy is oflavones and soy protein isolates containing isoflavones on bone health in rats and in humans is inconsistent and future studies are suggested to clarify the conditions under which these dietary substances can be helpful for bones.

TL;DR: This is the first efficacy trial using the novel technique of urinary 41Ca excretion from prelabeled bone to identify the effective dose of soy protein isolate enriched with isoflavones for suppressing bone resorption in postmenopausal women using a novel, rapid assessment of antibone resorbing treatments.

TL;DR: This study affirms that a single administration of either 3H-TC or 45Ca is a useful approach to measuring bone turnover directly and the amount of label incorporation into bone was greater in bone sites that were more metabolically active and in all sites when closer vs farther from OVX.

TL;DR: Urinary excretion of tritiated tetracycline and 41Ca tracers was validated as reflecting skeletal disappearance of these bone-seeking tracers as a direct measure of bone turnover following ovariectomy in rats.

TL;DR: To better understand (41)Ca technology as a tool for measuring effective treatments on reducing bone Resorption, perturbed bone resorption by manipulating dietary calcium in rats and found that a single dose is feasible to study bone resOrption.