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Showing papers by "Jennifer R. Hiscock published in 2014"

Journal Article•DOI•
Tripodal molecules for the promotion of phosphoester hydrolysis

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Jennifer R. Hiscock1, Mark R. Sambrook2, Philippa B. Cranwell1, Pat Watts2, Jack C. Vincent2, David J. Xuereb1, Neil J. Wells1, Robert Raja1, Philip A. Gale1 •
University of Southampton1, Salisbury University2
16 May 2014-Chemical Communications
TL;DR: A series of low molecular weight tripodal amide/histidine-containing compounds have been synthesised and shown to increase the rate of bis-(p-nitrophenyl) phosphate (BNPP) and soman (GD) breakdown in buffered aqueous solution.

22 citations

Journal Article•DOI•
Supramolecular gels for the remediation of reactive organophosphorus compounds

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Jennifer R. Hiscock1, Isabelle L. Kirby1, Julie Herniman1, G. John Langley1, Alistair J. Clark1, Philip A. Gale1 •
University of Southampton1
19 Sep 2014-RSC Advances
TL;DR: In this article, a cyclohexyl diamide gelator was used to simulate the organophosphorus (OP) chemical warfare agent (CWA) simulant diethyl chlorophosphate (DCP).
Abstract: Pyridine-based gels formed with a cyclohexyl diamide gelator have been shown to undergo a gel–sol transition upon addition of the organophosphorus (OP) chemical warfare agent (CWA) simulant diethyl chlorophosphate (DCP). This is due to a reaction between the gelator and DCP resulting in the disruption of the intermolecular hydrogen bonded gelator matrix and therefore the loss of gel stability. This selective phase change reliant on the presence of a reactive OP species provides a novel remediation and sensory method for this class of toxic compound.

15 citations