J
Jens Müller
Researcher at University Hospital Bonn
Publications - 79
Citations - 2731
Jens Müller is an academic researcher from University Hospital Bonn. The author has contributed to research in topics: Thrombin & Aptamer. The author has an hindex of 26, co-authored 76 publications receiving 2417 citations. Previous affiliations of Jens Müller include University of Strathclyde & University of Colorado Boulder.
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Vesicular trafficking, cytoskeleton and signalling in root hairs and pollen tubes.
TL;DR: The preferential localization of vesicles of the trans-Golgi network (TGN), defined by specific RAB GTPases, in the apical "clear zone" and the definition of TGN as a bona fide organelle involved in both polarized secretion and endocytosis.
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GFP-FABD2 fusion construct allows in vivo visualization of the dynamic actin cytoskeleton in all cells of Arabidopsis seedlings
Boris Voigt,Antonius C.J. Timmers,Jozef Šamaj,Jozef Šamaj,Jens Müller,František Baluška,Diedrik Menzel +6 more
TL;DR: A construct consisting of GFP fused to the C-terminal half of A. thaliana fimbrin 1 reveals dynamic arrays of F-actin in all cells of stably transformed A.Thaliana seedlings, which is essential for understanding the numerous roles of the actin cytoskeleton in diverse processes of cell differentiation.
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Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.
TL;DR: Genetic, pharmacological, molecular, cytological, and biochemical analyses suggest that ANP2/ANP3, MPK4, and the microtubule-associated protein MAP65-1 are all essential for the proper organization of cortical microtubules in Arabidopsis epidermal cells.
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Multidomain Targeting Generates a High-Affinity Thrombin-Inhibiting Bivalent Aptamer
TL;DR: This approach makes use of two functionally distinct aptamers that target the same protein, while the interaction of each aptamer is mediated by different protein subdomains.
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A new look at the microtubule binding patterns of dimeric kinesins.
Andreas Hoenger,Manfred Thormählen,Ruben Diaz-Avalos,Monika Doerhoefer,Kenneth N. Goldie,Jens Müller,Eckhard Mandelkow +6 more
TL;DR: This work reinvestigated the microtubule binding patterns of dimeric kinesins by cryo-EM and digital 3D reconstruction under different nucleotide conditions and different motor:tubulin ratios, and determined the molecular mass of motor-tubulin complexes by STEM.