Jeremy Cohen

TL;DR: Among patients with septic shock undergoing mechanical ventilation, a continuous infusion of hydrocortisone did not result in lower 90‐day mortality than placebo and there were no significant between‐group differences with respect to mortality at 28 days, the rate of recurrence of shock, the number of days alive and out of the ICU, the Recurrence of mechanical ventilation.

TL;DR: In western countries, injuries remain the leading cause of death in young adults and in developing countries road traffic injuries in particular are increasing in incidence and injuries are projected to be the third leadingCause of death and disability worldwide by 2020.

TL;DR: In adults with septic shock treated with low dose corticosteroids, short- and longer-term mortality are unaffected, adverse events increase, but duration of shock, mechanical ventilation and ICU stay are reduced.

TL;DR: In this paper, the authors randomly assigned patients with septic shock to receive hydrocortisone (at a dose of 200 mg per day) or placebo for 7 days or until death or discharge from the intensive care unit (ICU), whichever came first.

TL;DR: In this preliminary study, critical illness was associated with lower adiponectin concentrations as compared with controls, and a significant relationship between plasma cortisol and adip onectin in critically ill patients was evident, both during the early and late phases.