J
Jerry W. Simecka
Researcher at University of North Texas Health Science Center
Publications - 95
Citations - 3785
Jerry W. Simecka is an academic researcher from University of North Texas Health Science Center. The author has contributed to research in topics: Mycoplasma pulmonis & Immune system. The author has an hindex of 35, co-authored 95 publications receiving 3578 citations. Previous affiliations of Jerry W. Simecka include University of Alabama & University of North Texas System.
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Journal ArticleDOI
Biofilm Formation and Dispersal under the Influence of the Global Regulator CsrA of Escherichia coli
Debra W. Jackson,Kazushi Suzuki,Lawrence X. Oakford,Jerry W. Simecka,Mark E. Hart,Tony Romeo +5 more
TL;DR: It is established that the RNA binding global regulatory protein CsrA (carbon storage regulator) of Escherichia coli K-12 serves as both a repressor of biofilm formation and an activator ofBiofilm dispersal under a variety of culture conditions.
Journal ArticleDOI
Positive regulation of motility and flhDC expression by the RNA-binding protein CsrA of Escherichia coli
Bangdong L. Wei,Anne Marie Brun-Zinkernagel,Jerry W. Simecka,Birgit M. Prüß,Paul Babitzke,Tony Romeo +5 more
TL;DR: It is shown that the global regulator CsrA of E. coli K‐12 is necessary for motility under a variety of growth conditions, as a result of its role as an activator of flhDC expression.
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Catabolite repression of Escherichia coli biofilm formation.
TL;DR: A temporal role for cAMP in biofilm development was indicated by the finding that glucose addition after approximately 24 h failed to repress and generally activated biofilm formation.
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Intratracheal Gene Delivery with Adenoviral Vector Induces Elevated Systemic IgG and Mucosal IgA Antibodies to Adenovirus and β-Galactosidase
Frederik W. van Ginkel,Chongguang Liu,Jerry W. Simecka,Jian-Yun Dong,Terrence Greenway,Raymond A. Frizzell,Hiroshi Kiyono,Jerry R. McGhee,David W. Pascual +8 more
TL;DR: Evidence suggests that the lung and associated lymphoid tissues were the source for serum antibodies, and that the highest IgA spot-forming cell (SFC) response to Ade5 and beta-Gal was located in the NP and in the lung.
Journal ArticleDOI
Roles of Innate and Adaptive Immunity in Respiratory Mycoplasmosis
TL;DR: It is found that numbers of mycoplasmas in lungs were associated with genetic background (C3H susceptible, C57BL resistant) rather than functional state of adaptive immunity, indicating that innate immunity is the main contributor to antimyCoplasmal defense of the lungs.