J
Jessica A. Buckenberger
Researcher at Ohio State University
Publications - 4
Citations - 594
Jessica A. Buckenberger is an academic researcher from Ohio State University. The author has contributed to research in topics: Angiotensin II & microRNA. The author has an hindex of 4, co-authored 4 publications receiving 585 citations.
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Journal ArticleDOI
The Human Angiotensin II Type 1 Receptor +1166 A/C Polymorphism Attenuates MicroRNA-155 Binding
Mickey M. Martin,Jessica A. Buckenberger,Jinmai Jiang,Geraldine E. Malana,Gerard J. Nuovo,Maqsood A. Chotani,David S. Feldman,Thomas D. Schmittgen,Terry S. Elton +8 more
TL;DR: This study provides the first feasible biochemical mechanism by which the +1166 A/C polymorphism can lead to increased AT1R densities and possibly cardiovascular disease.
Journal ArticleDOI
MicroRNA-155 Regulates Human Angiotensin II Type 1 Receptor Expression in Fibroblasts
TL;DR: The studies suggest that miR-155 can bind to the 3'-untranslated region (UTR) of hAT(1)R mRNAs and translationally repress the expression of this protein in vivo.
Journal ArticleDOI
TGF-β1 stimulates human at1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways
Mickey M. Martin,Jessica A. Buckenberger,Jinmai Jiang,Geraldine E. Malana,Daren L. Knoell,David S. Feldman,Terry S. Elton +6 more
TL;DR: This study supports the hypothesis that a self-potentiating loop exists between the RAS and the TGF-beta1 signaling pathways and suggests that Angiotensin II and TGF -beta1 may cooperate in the pathogenesis of pulmonary fibrosis.
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TGF-β1 regulation of human AT1 receptor mRNA splice variants harboring exon 2.
TL;DR: The inclusion of exon 2 by alternative splicing represents a novel mechanism to reduce the overall production of the hAT(1)R protein and possibly limit the potential pathological effects of AT( 1)R activation.