Jessika Moreau

TL;DR: Both animal and human epidemiological studies support the idea that air pollutants cause defects during gametogenesis leading to a drop in reproductive capacities in exposed populations.

TL;DR: Environmental pollutants are probably a cause of premature ovarian insufficiency with an increased follicular depletion leading to an earlier age of menopause onset and the main mechanism seemed to be an increase in atresia of pre-antral follicles.

TL;DR: Sperm morphology assessment has very poor sensitivity and specificity in the diagnosis of infertility and in assisted reproductive technology, and there is very little evidence that indices of multiple sperm defects [sperm deformity index, teratozoospermia index, and multiple abnormalities index] are relevant.

TL;DR: Since it provides concordant results with a simplified method, the use of RECIST criteria is recommended for evaluation of treatment efficacy in clinical trials and routine practice.

TL;DR: The increased sperm aneuploidy observed in unexplained RPL supports a male etiology and pave the way for further studies to demonstrate the value of preimplantation genetic screening in men with increased spermAneuploidsy whose partners experience unexplained R PL.