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Jesús Martínez-Borra

Researcher at Services Hospital

Publications -  56
Citations -  2612

Jesús Martínez-Borra is an academic researcher from Services Hospital. The author has contributed to research in topics: Population & Human leukocyte antigen. The author has an hindex of 32, co-authored 55 publications receiving 2543 citations. Previous affiliations of Jesús Martínez-Borra include International Sleep Products Association.

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The MICA-A9 triplet repeat polymorphism in the transmembrane region confers additional susceptibility to the development of psoriatic arthritis and is independent of the association of Cw*0602 in psoriasis.

TL;DR: Independent of the HLA-C association, Mica-A9 polymorphism corresponding to the MICA-002 allele is a possible candidate gene for the development of PsA, consistent with the polygenic inheritance of psoriasis.
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TNF-α −308A promoter polymorphism is associated with enhanced TNF-α production and inflammatory activity in Crohn’s patients with fistulizing disease

TL;DR: TNF- alpha -308A polymorphism is associated with enhanced TNF-alpha production, more intense inflammatory activity, and an increased risk for arthritis susceptibility in CD patients with fistulizing disease.
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The relationship of anti-MICA antibodies and MICA expression with heart allograft rejection.

TL;DR: Following transplantation, MICA up‐regulation correlated with histological evidence of severe rejection and monitoring for MICA antibodies post‐transplant may be useful to establish new risk factors for acute rejection.