S
Sandra Rodríguez-Rodero
Researcher at University of Oviedo
Publications - 25
Citations - 925
Sandra Rodríguez-Rodero is an academic researcher from University of Oviedo. The author has contributed to research in topics: Population & Epigenetics. The author has an hindex of 15, co-authored 24 publications receiving 850 citations. Previous affiliations of Sandra Rodríguez-Rodero include International Sleep Products Association & Central University, India.
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Journal ArticleDOI
Protective Effect of the HLA-Bw4I80 Epitope and the Killer Cell Immunoglobulin-Like Receptor 3DS1 Gene against the Development of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Infection
Antonio López-Vázquez,Luis Rodrigo,Jesús Martínez-Borra,Ramón Pérez Pérez,Manuel Rodriguez,Juan Luis Fdez-Morera,Dolores Fuentes,Sandra Rodríguez-Rodero,Segundo Gonzalez,Carlos López-Larrea +9 more
TL;DR: It was found that the human leukocyte antigen-Bw4I80 epitope and the KIR3DS1 gene were more frequent in HCV carriers than in patients with hepatocellular carcinoma.
Journal ArticleDOI
DNA Methylation Signatures Identify Biologically Distinct Thyroid Cancer Subtypes
Sandra Rodríguez-Rodero,Agustín F. Fernández,Juan Luis Fernández-Morera,Patricia Castro-Santos,Gustavo F. Bayón,Cecilia Ferrero,Rocío G. Urdinguio,Rocío González-Márquez,Carlos Suárez,Iván Fernández-Vega,Manuel Florentino Fresno Forcelledo,Pablo Martínez-Camblor,Veronika Mancikova,Esmeralda Castelblanco,Marco Perez,Pablo Isidro Marrón,Marta Mendiola,David Hardisson,Pilar Santisteban,Garcilaso Riesco-Eizaguirre,Xavier Matias-Guiu,Amancio Carnero,Mercedes Robledo,Elías Delgado-Álvarez,Edelmiro Menéndez-Torre,Mario F. Fraga +25 more
TL;DR: Thyroid cancer subtypes present differential promoter methylation signatures, and nondifferentiated subtypes are characterized by aberrant promoter hypomethylation rather than hypermethylation.
Journal Article
Aging genetics and aging.
Sandra Rodríguez-Rodero,Juan Luis Fernández-Morera,Edelmiro Menéndez-Torre,Vincenzo Calvanese,Agustín F. Fernández,Mario F. Fraga +5 more
TL;DR: The process of aging refers to the decay of an organism's structure and function, in which molecular and cellular modifications can have various effects at the individual level over the course of a lifetime.
Journal ArticleDOI
Genetic and Non-genetic Predictors of LINE-1 Methylation in Leukocyte DNA.
Salman M. Tajuddin,Andre F.S. Amaral,Agustín F. Fernández,Sandra Rodríguez-Rodero,Ramon M. Rodriguez,Lee E. Moore,Adonina Tardón,Alfredo Carrato,Montserrat Garcia-Closas,Debra T. Silverman,Brian P. Jackson,Reina García-Closas,Ashley L. Cook,Kenneth P. Cantor,Stephen J. Chanock,Manolis Kogevinas,Nathaniel Rothman,Francisco X. Real,Francisco X. Real,Mario F. Fraga,Mario F. Fraga,Núria Malats +21 more
TL;DR: Several characteristics, environmental factors, and common genetic variants that predicted DNA methylation among study participants were identified.
Journal Article
Epigenetic regulation of aging.
Sandra Rodríguez-Rodero,Juan Luis Fernández-Morera,Agustín F. Fernández,Edelmiro Menéndez-Torre,Mario F. Fraga +4 more
TL;DR: Aging is one of the most challenging and unresolved problems in biology owing to its highly complex nature and epigenetics establishes the idea that the authors' health can be affected not only by the interplay of their genes and environment but also by the inherited effects of their ancestors' genes and environments.