J
Ji Wang
Researcher at University of California, San Francisco
Publications - 16
Citations - 1293
Ji Wang is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Gene expression & Regulation of gene expression. The author has an hindex of 14, co-authored 16 publications receiving 1173 citations.
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Journal ArticleDOI
Upregulation of Cyclin B1 by miRNA and its implications in cancer
Vera Huang,Robert F. Place,Victoria Portnoy,Ji Wang,Zhongxia Qi,Zhe-Jun Jia,Angela J. Yu,Marc A. Shuman,Jingwei Yu,Long-Cheng Li +9 more
TL;DR: The findings reveal an endogenous system by which miRNA functions to activate Ccnb1 expression in mouse cells and manipulate in vivo tumor development/growth.
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Pseudogene PTENP1 Functions as a Competing Endogenous RNA to Suppress Clear-Cell Renal Cell Carcinoma Progression
Gan Yu,Weimin Yao,Kiranmai Gumireddy,Anping Li,Ji Wang,Wei Xiao,Ke Chen,Haibing Xiao,Heng Li,Kun Tang,Zhangqun Ye,Qihong Huang,Hua Xu +12 more
TL;DR: It is suggested that PTENP1 functions as a competing endogenous RNA (ceRNA) in ccRCC to suppress cancer progression and recapitulating the phenotypes induced by PTEN expression.
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RNAa is conserved in mammalian cells.
Vera Huang,Yi Qin,Ji Wang,Xiaoling Wang,Robert F. Place,Guiting Lin,Tom F. Lue,Long-Cheng Li +7 more
TL;DR: This study demonstrates that RNAa exists in mammalian species other than human, and suggests that nonhuman primate disease models may have clinical applicability for validating RNAa-based drugs.
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Prognostic Value and Function of KLF4 in Prostate Cancer: RNAa and Vector-Mediated Overexpression Identify KLF4 as an Inhibitor of Tumor Cell Growth and Migration
Ji Wang,Robert F. Place,Vera Huang,Xiaoling Wang,Emily J. Noonan,Clara E. Magyar,Jiaoti Huang,Long-Cheng Li +7 more
TL;DR: The results suggest that KLF4 functions as an inhibitor of tumor cell growth and migration in prostate cancer and decreased expression has prognostic value for predicting prostate cancer metastasis.
Journal ArticleDOI
Ago1 Interacts with RNA Polymerase II and Binds to the Promoters of Actively Transcribed Genes in Human Cancer Cells
Vera Huang,Jiashun Zheng,Zhongxia Qi,Ji Wang,Robert F. Place,Jingwei Yu,Hao Li,Long-Cheng Li +7 more
TL;DR: This study combines ChIP-seq (chromatin immunoprecipitation coupled with massively parallel sequencing) with biochemical assays to show that nuclear Ago1 directly interacts with RNA Polymerase II and is widely associated with chromosomal loci throughout the genome with preferential enrichment in promoters of transcriptionally active genes.