Jiaoti Huang

TL;DR: The classification working group of the International Society of Urological Pathology consensus conference on renal neoplasia was in charge of making recommendations regarding additions and changes to the current World Health Organization Classification of Renal Tumors, with consensus that 5 entities should be recognized as new distinct epithelial tumors within the classification system.

TL;DR: It is proposed that heparin causes oligomerization of aFGF such that its binding to FGFR results in dimerization and activation, which represents a novel mechanism for transmembrane signaling and may account for the action of many heParin-bound growth factors.

TL;DR: In this paper, a variety of enrichment mechanisms such as immunomagnetic separation based on capture agent-labeled magnetic beads, microfluidics-based technologies that enhance cell-surface contacts, and microfilter devices that isolate CTCs based on size difference are proposed.

TL;DR: The International Society of Urological Pathology 2012 Consensus Conference made recommendations regarding classification, prognostic factors, staging, and immunohistochemical and molecular assessment of adult renal tumors.

TL;DR: PTP 1D was phosphorylated on tyrosine in cells overexpressing the beta PDGF receptor kinase and this tyrosin phosphorylation correlated with an enhancement of its catalytic activity, suggesting that protein tyrosines and phosphatases may work in concert to maintain a fine balance of effector activation needed for the regulation of cell growth and differentiation.