J
Ji Wang
Researcher at China Pharmaceutical University
Publications - 7
Citations - 193
Ji Wang is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Nanocarriers & Nimodipine. The author has an hindex of 6, co-authored 7 publications receiving 166 citations. Previous affiliations of Ji Wang include Fourth Military Medical University.
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Journal ArticleDOI
Pharmacokinetics and atherosclerotic lesions targeting effects of tanshinone IIA discoidal and spherical biomimetic high density lipoproteins.
TL;DR: In this paper, Discoidal and spherical recombinant HDL loaded with cardiovascular drug tanshinone IIA (TA) were constructed (TA-d-rHDL and TA-s-RHDL), and their in vitro physiochemical and biomimetic properties were characterized.
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Tumor targeting effects of a novel modified paclitaxel-loaded discoidal mimic high density lipoproteins
TL;DR: In this article, the authors developed a novel biomimetic nanocarriers that were developed for tumor targeting delivery to avoid unexpected drug leakage from discoidal reconstituted high density lipoproteins (d-rHDL) during remodeling process associated with lecithin-cholesterol acyltransferase (LCAT).
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Liquid Proliposomes of Nimodipine Drug Delivery System: Preparation, Characterization, and Pharmacokinetics
TL;DR: NPSC offered a potential way to improve oral delivery of nimodipine and presented similar pharmacokinetic parameters compared with NPSC.
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Arachidonic acid-modified lovastatin discoidal reconstituted high density lipoprotein markedly decreases the drug leakage during the remodeling behaviors induced by lecithin cholesterol acyltransferase.
Hongliang He,Lisha Liu,Hui Bai,Ji Wang,Yan Zhang,Wenli Zhang,Mengyuan Zhang,Zimei Wu,Jianping Liu +8 more
TL;DR: With increment of AA modification amount, AA-LT-d-rHDL manifested lower reactivity with LCAT, thus significantly reducing the undesired drug leakage during the remodeling behaviors induced by LCAT.
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A Simple Method to Extract Whole Apolipoproteins for the Preparation of Discoidal Recombined High Density Lipoproteins as Bionic Nanocarriers for Drug Delivery.
TL;DR: Sterol efflux assay from macrophages mediated by TA-rHDLs and structure remodeling behavior from discs to spheres proved that TA- rHDL could resemble the biological activity of native nascent HDL irrespective of the size.