J
Jianli Ma
Researcher at Chinese PLA General Hospital
Publications - 12
Citations - 695
Jianli Ma is an academic researcher from Chinese PLA General Hospital. The author has contributed to research in topics: Self-healing hydrogels & Drug delivery. The author has an hindex of 9, co-authored 12 publications receiving 585 citations.
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Drug nanocrystals: In vivo performances
TL;DR: In vivo performances of drug nanocrystals exhibited in animals in different administration route were reviewed, and the advantages of drug Nanocrystals in the aspect of safety, pharmacodynamics, pharmacokinetics and targeting delivery were discussed in detail.
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Application of Drug Nanocrystal Technologies on Oral Drug Delivery of Poorly Soluble Drugs
TL;DR: The in vivo performances of oral drug nanocrystals exhibited in animals related to the pharmacokinetic, efficacy and safety characteristics were described and the technologies and evaluation associated with the solidification process of the drug Nanocrystals suspensions were discussed in detail.
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The application of mucoadhesive polymers in nasal drug delivery.
TL;DR: The mucoadhesive polymers have enormous potential for the delivery of therapeutic macromolecules, genes, and vaccines through the nasal cavity with high drug bioavailability.
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Paclitaxel nanosuspensions coated with P-gp inhibitory surfactants: I. Acute toxicity and pharmacokinetics studies
TL;DR: The paclitaxel nanosuspensions prepared in this study could markedly enhance the tolerance dosage in mice, and manifest different pharmacokinetic properties compared with the solution.
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Paclitaxel nanosuspension coated with P-gp inhibitory surfactants: II. Ability to reverse the drug-resistance of H460 human lung cancer cells.
TL;DR: The usage of TPGS as stabilizers on the surface of nanocrystals of insoluble anticancer drugs may be an effective approach to overcome the multi-drug resistances (MDR).