J
Jianping Liu
Researcher at China Pharmaceutical University
Publications - 125
Citations - 2640
Jianping Liu is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 24, co-authored 99 publications receiving 1975 citations.
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A quality by design (QbD) case study on enteric- coated pellets: Screening of critical variables and establishment of design space at laboratory scale
TL;DR: In this article, the authors used failure mode and effect analysis (FMEA) methodology to assess the most important variables affecting enteric-coated pellets characteristics, and a Box-Behnken design was subsequently used for investigating the main, interactive, and quadratic effects of these variables on the response.
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Preparation and Pharmacokinetic Evaluation of Tashinone IIA Solid Lipid Nanoparticles
TL;DR: The results of pharmacokinetic studies in rabbits indicated that the formulation of TA-SLN was successful in providing a delivery of slow release of Tashinone IIA.
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Strategies to enhance drug delivery to solid tumors by harnessing the EPR effects and alternative targeting mechanisms.
TL;DR: In this article , the authors discussed strategies to augment Enhanced Permeability and Retention (EPR) mediated tumor-mediated tumoral delivery in different dimensions including enhancement of vascular permeability, depletion of tumor extracellular matrix and optimization of nanoparticle design.
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Multifunctional Dextran Sulfate-Coated Reconstituted High Density Lipoproteins Target Macrophages and Promote Beneficial Antiatherosclerotic Mechanisms.
TL;DR: Collectively, AT-DXS-LP-rHDL, as multifunctional carriers, could not only deliver more drug to macrophages, but also present antiatherogenic actions of the biofunctional nanocarriers through damping oxidized low density lipoproteins (oxLDL) uptake and promoting cholesterol efflux.
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Recent advances in the development of polyethylenimine-based gene vectors for safe and efficient gene delivery.
TL;DR: Further optimization by combining the two strategies is needed for the maximized transfection efficiency and minimized side effects, shedding new light on the development of nonviral gene delivery for clinical application.