J
Jianping Liu
Researcher at China Pharmaceutical University
Publications - 125
Citations - 2640
Jianping Liu is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 24, co-authored 99 publications receiving 1975 citations.
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Journal Article
Stealth tanshinone IIA-loaded solid lipid nanoparticles: effects of poloxamer 188 coating on in vitro phagocytosis and in vivo pharmacokinetics in rats.
TL;DR: Phagocytosis studies showed significant differences between TA-SSLNs and TA-NSLNs and demonstrated that the poloxamer 188 coating could decrease the macrophage uptake and AUC of tanshinone IIA increased as a function of SLNs.
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Fabrication of TPGS-Stabilized Liposome-PLGA Hybrid Nanoparticle Via a New Modified Nanoprecipitation Approach: In Vitro and In Vivo Evaluation
TL;DR: Findings suggest the modified nanoprecipitation method holds great potential for fabricating LPN, aided by the multiple functions of TPGS, and the prepared TLPN is a promising delivery system for use in the pharmaceutical field.
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A novel modified paclitaxel-loaded discoidal recombinant high-density lipoproteins: Preparation, characterizations and in vivo evaluation
TL;DR: It is demonstrated that cP-d-rHDLs, whose remodeling behaviors were restrained effectively after structural modification, exhibited more excellent and promising properties as novel delivery vehicles for anti-cancer agents.
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Physicochemical characterization of asulacrine towards the development of an anticancer liposomal formulation via active drug loading: Stability, solubility, lipophilicity and ionization
Esther See,Wenli Zhang,Jianping Liu,Darren Svirskis,Bruce C. Baguley,John Shaw,Guangji Wang,Zimei Wu +7 more
TL;DR: The obtained physicochemical parameters provided insightful information useful to maximise DL into the liposomes, and explain a tendency of drug precipitation of pH-solubilized formulations following intravenous infusion.
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Evaluation of pharmacokinetic and pharmacodynamic relationship for oral sustained-release atenolol pellets in rats.
TL;DR: The more favorable characteristics of SRPs would make it more appropriate as a potential dosage form for the treatment of hypertension.