J
Jie Ji
Researcher at Nanjing Medical University
Publications - 15
Citations - 1059
Jie Ji is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Carcinogenesis & DNA methylation. The author has an hindex of 11, co-authored 14 publications receiving 833 citations. Previous affiliations of Jie Ji include Nanjing University.
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Journal ArticleDOI
The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion.
Runqiu Jiang,Junwei Tang,Yun Chen,Lei Deng,Jie Ji,Yu Xie,Ke Wang,Wei Jia,Wen-Ming Chu,Beicheng Sun +9 more
TL;DR: It is shown that lnc-epidermal growth factor receptor (EGFR) upregulation in Tregs correlates positively with the tumour size and expression of EGFR/Foxp3, but negatively with IFN-γ expression in patients and xenografted mouse models.
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HULC and Linc00152 Act as Novel Biomarkers in Predicting Diagnosis of Hepatocellular Carcinoma.
TL;DR: The results suggest that both plasma levels of HULC and Linc00152 achieve a fine diagnostic accuracy in diagnosing ontogenesis and metastasis of HCC and may act as novel biomarkers for HCC.
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LINC00152 promotes proliferation in hepatocellular carcinoma by targeting EpCAM via the mTOR signaling pathway.
TL;DR: Microarray-based analysis indicated that LINC00152 could activate the mechanistic target of rapamycin(mTOR) pathway by binding to the promoter of EpCAM through a cis-regulation, as confirmed by Gal4-λN/BoxB reporter system.
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The aberrant expression of MEG3 regulated by UHRF1 predicts the prognosis of hepatocellular carcinoma
TL;DR: MEG3, acting as a potential biomarker in predicting the prognosis of HCC, was regulated by UHRF1 via recruiting DNMT1 and regulated p53 expression.
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Long non-coding RNA Lnc-Tim3 exacerbates CD8 T cell exhaustion via binding to Tim-3 and inducing nuclear translocation of Bat3 in HCC.
Jie Ji,Yin Yin,Huanyu Ju,Xiaoliang Xu,Wei Liu,Qiang Fu,Jiaojiao Hu,Xudong Zhang,Beicheng Sun +8 more
TL;DR: It is shown that Lnc-Tim3 is upregulated and negatively correlates with IFN-γ and IL-2 production in tumor-infiltrating CD8 T cells of HCC patients, suggesting that LngRNA and its associated signaling pathways may influence the outcome of cancer therapies aimed at modulating the acquired immune system.