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Wenjie Zhang
Researcher at Nanjing University
Publications - 35
Citations - 1131
Wenjie Zhang is an academic researcher from Nanjing University. The author has contributed to research in topics: Medicine & PI3K/AKT/mTOR pathway. The author has an hindex of 14, co-authored 29 publications receiving 748 citations. Previous affiliations of Wenjie Zhang include Yangzhou University & Nanjing Medical University.
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Journal ArticleDOI
HULC and Linc00152 Act as Novel Biomarkers in Predicting Diagnosis of Hepatocellular Carcinoma.
TL;DR: The results suggest that both plasma levels of HULC and Linc00152 achieve a fine diagnostic accuracy in diagnosing ontogenesis and metastasis of HCC and may act as novel biomarkers for HCC.
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miR-874 Inhibits cell proliferation, migration and invasion through targeting aquaporin-3 in gastric cancer.
Baofei Jiang,Zengliang Li,Wenjie Zhang,Haixiao Wang,Xiaofei Zhi,Jin Feng,Zheng Chen,Yi Zhu,Li Yang,Hao Xu,Zekuan Xu +10 more
TL;DR: Functional analyses indicated that ectopic miR-874 expression suppressed the growth, migration, invasion and tumorigenicity of GC cells, whereas miR -874 knockdown promoted these phenotypes.
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14-3-3ζ delivered by hepatocellular carcinoma-derived exosomes impaired anti-tumor function of tumor-infiltrating T lymphocytes.
Xiaochen Wang,Haiyuan Shen,Guangyan Zhangyuan,Ruyi Huang,Wenjie Zhang,Qifeng He,Kangpeng Jin,Han Zhuo,Zechuan Zhang,Jin-Cheng Wang,Beicheng Sun,Beicheng Sun,Xiao-Jie Lu +12 more
TL;DR: It is demonstrated for the first time that 14-3-3ζ expression was up-regulated in and inhibited the anti-tumor functions of tumor-infiltrating T cells in HCC microenvironment and that 14,3- 3ζ might be transmitted from HCC cells to T cells at least partially through exosomes.
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Down-Regulation of LncRNA DGCR5 Correlates with Poor Prognosis in Hepatocellular Carcinoma.
Ruyi Huang,Xiaochen Wang,Wenjie Zhang,Guangyan Zhangyuan,Kangpeng Jin,Weiwei Yu,Yu Xie,Xiaoliang Xu,Hai Wang,Beicheng Sun +9 more
TL;DR: The results suggest that DGCR5 may be a participator in HCC and can serve as potential biomarker for the diagnosis and prognosis in H CC.
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IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma
TL;DR: Investigation of the relationship between decreased PTPRO and increased programmed death ligand 1 (PD-L1) in both the peripheral monocytes and tumor-infiltrating macrophages of human hepatocellular carcinoma found a significant decrease in PTPRO in HCC peripheral monocyte that was associated with increased PD-L 1 expression.