Jin Ho Oh

TL;DR: It is observed that greater than 99% of leukocytes in whole blood were effectively removed at an optimal centrifugal force, due to differences in their sedimentation rates, yielding a much purer sample compared to other filter-based methods.

TL;DR: A novel approach for isolation and subsequent in situ protein-expression analysis of CTCs is demonstrated using detachable beads termed RIA (reversible bead attachment for cell isolation and analysis), demonstrating the incompatibility of in situ quantitative analysis with bead-based capture methods.

TL;DR: A novel centrifugal microfluidic platform that can isolate the rare cells from a large volume of whole blood and performs epidermal growth factor receptor (EGFR) mutation analysis with HCC827 lung cancer cells and the isolated cells were successfully detected for the mutation by PCR clamping and direct sequencing.

TL;DR: Using hybrid nanoparticles (HNPs), it is possible to count, analyze in situ protein expression, and culture CTCs, all from the same set of cells, enabling a wide range of molecular- and cellular-based studies using C TCs.

TL;DR: A microchip filter device incorporating slit arrays and 3-dimensional flow that can separate heterogeneous population of cells with marker for CTCs is reported, enabling the enhanced capture yield from metastatic breast cancer patients and obtained cells that expressed various EMT markers.