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Showing papers in "Biosensors and Bioelectronics in 2013"


Journal ArticleDOI
TL;DR: In this study, a sensor for the detection of glucose and hydrogen peroxide was developed on the basis of Cu2O nanocubes wrapped by graphene nanosheets (Cu2O/GNs) as electrocatalysts with high sensitivity and selectivity, improved stability and fast amperometric response.

660 citations


Journal ArticleDOI
TL;DR: The Fe3O4/r-GO hybrid presented here showing favorable electrochemical features may hold great promise to the development of electrochemical sensors, molecular bioelectronic devices, biosensors and biofuel cells.

450 citations


Journal ArticleDOI
TL;DR: A review of the state-of-the-art in detection of markers associated with wound healing and infection, utilizing devices imbedded within dressings or as point of care techniques to allow for continual or rapid wound assessment and monitoring is presented in this article.

366 citations


Journal ArticleDOI
TL;DR: The accurate glucose determination in human blood serum and good recoveries achieved in spiked urine samples revealed their great potential in the practical applications.

317 citations


Journal ArticleDOI
TL;DR: The facile and easy electrochemical approach used for the preparation of RGO-GOx may open up new horizons in the production of cost-effective biosensors and biofuel cells.

305 citations


Journal ArticleDOI
TL;DR: The developed biosensor responds efficiently to glucose presence over the concentration range 5-1270 μM with the detection limit 1.73 μM (S/N=3) and sensitivity 0.085 μA μM(-1) cm(-2), attributed to the large surface-to-volume ratio, excellent biocompatibility of GQD, porosity of G QD|CCE, and the abundance of hydrophilic edges as well as hydrophobic plane in

287 citations


Journal ArticleDOI
TL;DR: A carbon paste electrode modified with 4-ethylbenzene-1, 2-diol and NiO/CNTs nanocomposite was used for the sensitive voltammetric determination of cysteamine, nicotinamide adenine dinucleotide and folic acid for the first time.

265 citations


Journal ArticleDOI
TL;DR: The prepared modified electrode shows several advantages such as simple preparation method, high sensitivity, high stability, ease of preparation and regeneration of the electrode surface by simple polishing along with excellent reproducibility.

258 citations


Journal ArticleDOI
TL;DR: The use of gold nanoparticles (AuNPs) as labeling carriers in combination with the enzymatic activity of the horseradish peroxidase (HRP) in order to achieve an improved optical lateral flow immunoassay (LFIA) performance is presented here.

256 citations


Journal ArticleDOI
TL;DR: This review focuses on the three most conventional site-directed antibody immobilization techniques used in immunosensor design, based on the use of chemically or genetically engineered antibody fragments attached to the sensor surface covered in gold or self-assembled monolayer via the sulfhydryl groups present in the hinge region.

250 citations


Journal ArticleDOI
TL;DR: An easy prepared fluorometric and colorimetric dual channel probe is developed for dopamine (DA) detection with high sensitivity and selectivity by use of BSA-stabilized Au nanoclusters (BSA-AuNCs).

Journal ArticleDOI
TL;DR: This review adumbrates the significant requirements of anodes that are essential to be fulfilled, encompasses the aspiring research efforts which have been devoted so far in the anode modification and fabrication strategies to increase the power output, durability and compatibility of the anodes interface with the inoculated microorganisms.

Journal ArticleDOI
TL;DR: The Au-SH-SiO₂@Cu-MOF showed a very efficient electrocatalytic activity for the oxidation of L-cysteine in 0.1 M phosphate buffer solution (pH 5.0).

Journal ArticleDOI
Yanbo Zeng1, Ying Zhou1, Lei Kong1, Tianshu Zhou1, Guoyue Shi1 
TL;DR: The sensor based on this novel imprinted composite was applied to the determination of DA in injections and human urine samples with satisfactory results and could recognize DA from its relatively similar molecules of norepinephrine and epinephrine, while the sensors based on GO/SiO2-NIPs and vinyl groups functionalized GO/ SiO2 did not have the ability.

Journal ArticleDOI
TL;DR: This review aims to highlight current trends in biosensors for glucose monitoring based on nanotechnology, reporting widespread representative examples of the recent approaches for nanobiosensors over the past 10 years.

Journal ArticleDOI
TL;DR: This review discusses the current state of electrochemical biosensors in the determination of mycotoxins in foods and covers complete literature from the first reports about sixteen years ago.

Journal ArticleDOI
TL;DR: GO is a promising fluorescent probe for detection of metal ions and biomolecules and shows a limit of detection as low as 0.92 nM and excellent selectivity toward Hg(2+) over a wide range ofMetal ions.

Journal ArticleDOI
TL;DR: The experiments have provided direct evidence that the fluorescence of QDs is quenched by GO via the nano-metal surface energy transfer (NSET) mechanism rather than the conventional Förster resonanceEnergy transfer (FRET) process.

Journal ArticleDOI
TL;DR: An optical system and image analysis algorithm based upon a cell phone platform able to provide point-of-care quantitative TSH results with a high level of sensitivity and reproducibility comparable to that of a clinical laboratory-based third-generation TSH immunoassay is developed.

Journal ArticleDOI
TL;DR: A double signal amplification platform for ultrasensitive and simultaneous detection of ascorbic acid, dopamine, uric acid and acetaminophen was fabricated by a nanocomposite of ferrocene thiolate stabilized Fe₃O₄@Au nanoparticles with graphene sheet with synergistic catalytic and amplification effect toward AA, DA, UA and AC oxidation.

Journal ArticleDOI
TL;DR: Progress in the development of phosphate sensors, designed for use in a variety of disciplines, is highlighted and the need for long term stability, low maintenance, specificity and the capability of measuring total phosphorus concentrations down to at least 1 mg/l is considered, as required by legislation.

Journal ArticleDOI
TL;DR: The recent achievements and progress in developing EIs towards point of care (POC) diagnostics are reviewed.

Journal ArticleDOI
TL;DR: The results showed that the developed hydrogel QCM aptasensor was capable of detecting target H5N1 virus, and among the three developed aptamer hydrogels, Hydrogel III coated QCMaptasensor achieved the highest sensitivity with the detection limit of 0.0128 HAU (HA unit).

Journal ArticleDOI
TL;DR: The R-GO FET biosensor showed a high specificity to other cancer biomarker in the phosphate buffered saline solutions as well as in the human serum, and can detect protein-protein interactions down to femtomolar level with a dynamic range over 6-orders of magnitude in the V(g,min) shift as a sensitivity parameter.

Journal ArticleDOI
TL;DR: The proposed one-step, label-free method was successfully used to determine BPA in actual water samples and met the various detection requirements for BPA and are comparable to the traditional ELISA and instrument-based methods.

Journal ArticleDOI
TL;DR: A sensitive, label-free, non-amplified and reusable electrochemical impedimetric biosensor for the detection of CRP in blood serum was developed herein based on controlled and coverage optimised antibody immobilization on standard polycrystalline gold electrodes.

Journal ArticleDOI
TL;DR: The aim of this review is to summarise the main achievements attained so far and to initialise researchers in the field of antibody-based assays employing QDs as labels, such as fluorescence-linked immunosorbent assay (FLISA), fluorescence (or Förster) resonance energy transfer (FRET), immunochromatographic methods, and immunosensors.

Journal ArticleDOI
TL;DR: This study reports the construction of a set of scalable synthetic microbe-based biosensors comprising exchangeable sensory, signal processing and actuation modules and demonstrates how a modular cell- based biosensor can be engineered predictably using exchangeable synthetic gene circuit modules to sense and integrate multiple-input signals.

Journal ArticleDOI
TL;DR: It is demonstrated that the sensing performance of the graphene samples prepared by gold-transfer is largely enhanced, which is more sensitive than the existing report based on few-layer graphene.

Journal ArticleDOI
TL;DR: A highly sensitive and selective biomimetic electrochemical sensor for the amperometric detection of trace dopamine (DA) in human serums was achieved by gold nanoparticles (AuNPs) doped molecularly imprinted polymers (MIPs).