https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.22759

Diagnosis, management, and treatment of hepatitis C: An update

https://aasldpubs.onlinelibrary.wiley.com/doi/epdf/10.1002/hep.20119

Diagnosis, Management, and Treatment of Hepatitis C

Objective: The authors investigated the unique contribution motivational interviewing (MI) has on counseling outcomes and how MI compares with other interventions. Method: A total of 119 studies we...

A Meta-Analysis of Motivational Interviewing: Twenty-Five Years of Empirical Studies.

Ontario HIV Treatment
Network; Canadian Institutes for Health Research; National Institues of Health (AI005535901, K23A106858201, AA015287, MH54907, AI27763); British Columbia Michael Smith Foundation; The Doris Duke Charitable Foundation

https://www.ghdonline.org/uploads/Adherence_to_HAART_A_Systematic_Review_of_Developed_and_Developing_Nation_Patient-Reported_Barriers_and_Facilitators_.pdf

Adherence to HAART: A Systematic Review of Developed and Developing Nation Patient-Reported Barriers and Facilitators

RESULTS Seventy-eight percent of patients in the buprenorphine group (89 of 114 [95% CI, 70%-85%]) vs 37% in the referral group (38 of 102 [95% CI, 28%-47%]) and 45% in the brief intervention group (50 of 111 [95% CI, 36%-54%]) were engaged in addiction treatment on the 30th day after randomization (P < .001). The buprenorphine group reduced the number of days of illicit opioid use per week from 5.4 days (95% CI, 5.1-5.7) to 0.9 days (95% CI, 0.5-1.3) vs a reduction from 5.4 days (95% CI, 5.1-5.7) to 2.3 days (95% CI, 1.7-3.0) in the referral group and from 5.6 days (95% CI, 5.3-5.9) to 2.4 days (95% CI, 1.8-3.0) in the brief intervention group (P < .001 for both time and intervention effects; P = .02 for the interaction effect). The rates of urine samples that tested negative for opioids did not differ statistically across groups, with 53.8% (95% CI, 42%-65%) in the referral group, 42.9% (95% CI, 31%-55%) in the brief intervention group, and 57.6% (95% CI, 47%-68%) in the buprenorphine group (P = .17). There were no statistically significant differences in HIV risk across groups (P = .66). Eleven percent of patients in the buprenorphine group (95% CI, 6%-19%) used inpatient addiction treatment services, whereas 37% in the referral group (95% CI, 27%-48%) and 35% in the brief intervention group (95% CI, 25%-37%) used inpatient addiction treatment services (P < .001).

/pdf/emergency-department-initiated-buprenorphine-naloxone-1ksvm2aubu.pdf

Emergency Department–Initiated Buprenorphine/Naloxone Treatment for Opioid Dependence: A Randomized Clinical Trial

Hepatitis C disease among injection drug users : knowledge, perceived risk and willingness to receive treatment

Depression among needle exchange program and methadone maintenance clients.

Methadone maintenance patients infected with human immunodeficiency virus (HIV) currently receiving antiretroviral therapy had HIV RNA testing and were surveyed regarding their adherence to their t...

Adherence to Antiretroviral Therapy Among HIV-Infected Methadone Patients: Effect of Ongoing Illicit Drug Use*

Aims To test motivational interviewing (MI) as a brief intervention for reducing alcohol use among needle exchange clients.



Design Randomized clinical trial.



Setting Needle exchange program—Providence, Rhode Island, USA.



Participants Between 2/98 and 10/99, we recruited 187 AUDIT-positive (>8) active injection drug users.



Intervention Those assigned to a brief motivational intervention (MI) condition received two 1-hour therapist sessions following assessment visits, 1 month apart, focusing on alcohol use and HIV risk-taking.



Measurements Control and MI subjects received identical research assessments at baseline, 1 and 6 months following study enrollment. At 6 months, study outcomes included days of alcohol use measured using the time-line follow-back method.



Findings Study retention was 96.8% at 6 months. Participants reported an average of 12.0 drinking days at baseline and 8.3 at 6 months. Significant reductions in drinking days were observed in both treatment conditions. We found significant treatment × baseline drinking day interaction effects. Tests for simple main effects were significant for subjects with above median (>9) baseline drinking day frequency, but not for those with below median baseline drinking frequency. Comparisons on dichotomous outcomes provided supporting evidence of treatment efficacy; those in MI were over two times more likely than controls to report reductions of 7 days or more (P < 0.05).



Conclusions This study provides the first direct evidence that brief MI can decrease alcohol use among active injection drug users with drinking problems. Heavier drinkers seem best suited for this intervention, but the optimal intensity of treatments and which components of brief intervention are most effective deserve further study.

Jina Maksad

Papers

Hepatitis C disease among injection drug users : knowledge, perceived risk and willingness to receive treatment

Depression among needle exchange program and methadone maintenance clients.

Adherence to Antiretroviral Therapy Among HIV-Infected Methadone Patients: Effect of Ongoing Illicit Drug Use*

A randomized trial of a brief alcohol intervention for needle exchangers (BRAINE).