J
Jing Zhang
Researcher at Fudan University
Publications - 4
Citations - 72
Jing Zhang is an academic researcher from Fudan University. The author has contributed to research in topics: Influenza A virus & PKM2. The author has an hindex of 3, co-authored 4 publications receiving 41 citations.
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Journal ArticleDOI
Influenza A virus (H1N1) triggers a hypoxic response by stabilizing hypoxia-inducible factor-1α via inhibition of proteasome.
Lehao Ren,Wanju Zhang,Peng Han,Jiaxiang Zhang,Yong Zhu,Xiaoxiao Meng,Jing Zhang,Yunwen Hu,Zhigang Yi,Ruilan Wang +9 more
TL;DR: Findings reveal a previously unrecognized mechanism of viral activation of the HIF-1 pathway, resembling a hypoxic response in normoxia.
Journal ArticleDOI
Influenza A Virus (H1N1) Infection Induces Glycolysis to Facilitate Viral Replication
Lehao Ren,Lehao Ren,Wanju Zhang,Jing Zhang,Jiaxiang Zhang,Huiying Zhang,Yong Zhu,Xiaoxiao Meng,Zhigang Yi,Ruilan Wang +9 more
TL;DR: In this article, the authors observed that influenza A virus (H1N1), a single-stranded, negative-sense RNA virus with an eight-segmented genome, enhanced glycolysis both in mouse lung tissues and in human lung epithelial (A549) cells.
Journal ArticleDOI
Astragaloside IV attenuates IL-1β secretion by enhancing autophagy in H1N1 infection.
Jing Zhang,Wanju Zhang,Lehao Ren,Yanchao He,Zhoufang Mei,Jingjing Feng,Tianyun Shi,Huiying Zhang,Zhigang Song,Zhijun Jie +9 more
TL;DR: It was found that AS-IV promoted H1N1-triggered formation of autophagosomes and autolysosomes and it may lead to the decreased IL-1β secretion.
Journal ArticleDOI
An infectious clone of enterovirus 71(EV71) that is capable of infecting neonatal immune competent mice without adaptive mutations.
Huiying Zhang,Zhigang Song,Jingyi Zou,Yanling Feng,Jing Zhang,Lehao Ren,Xiaonan Zhang,Yunwen Hu,Zhenghong Yuan,Zhigang Yi +9 more
TL;DR: A stable EV71 infectious clone is generated that is capable of infecting neonatal immune competent mice without adaptive mutations and provide a simple, valuable animal model for the studies of EV71pathogenesis and therapy.