J
Jinjun Liu
Publications - 3
Citations - 31
Jinjun Liu is an academic researcher. The author has contributed to research in topics: Calanolide A & Luche reduction. The author has an hindex of 3, co-authored 3 publications receiving 31 citations.
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Patent
Method for the preparation of (+)-calanolide a and analogues thereof
Michael T. Flavin,Ze-Qi Xu,Albert Khilevich,David E. Zembower,John D. Rizzo,Shuyuan Liao,Aye Aye Mar,Lin Lin,Vilayphone Vilaychack,Darko Brankovic,Sergey Dzekhster,Jinjun Liu +11 more
TL;DR: In this paper, a method of preparing (+)-calanolide A, 1, a potent HIV reverse transcriptase inhibitor, from chromene 4 is provided, where the intermediate was subjected to a chlorotitanium-mediated aldol reaction with acetaldehyde to selectively produce (±)-8a.
Journal ArticleDOI
A Versatile Approach for Synthesis of 2,3-Dimethyl Chroman-4-ones, Intermediate for Calanolide Anti-HIV Agents, VIA Aldol/Mitsunobu Reactions
Albert Khilevich,John D. Rizzo,Michael T. Flavin,Abram Kivovich Sheinkman,Aye Aye Mar,Alla Kucherenko,Changren Yan,Sergey Dzekhtser,Darko Brankovic,Lin Lin,Jinjun Liu,Thomas M. Rizzo,Ze-Qi Xu +12 more
TL;DR: Combined aldol/Mitsunobu reactions have been employed for the first time for synthesis of 2,3-dimethyl chroman-4-ones, intermediates for calanolide anti-HIV agents.
Patent
calanolide A and analogues thereof
Michael T. Flavin,Ze-Qi Xu,Albert Khilevich,David E. Zembower,John D. Rizzo,Shuyuan Liao,Aye Aye Mar,Lin Lin,Vilayphone Vilaychack,Darko Brankovic,Sergey Dzekhster,Jinjun Liu +11 more
TL;DR: In this article, a method of preparing (+)-calanolide A, 1, a potent HIV reverse transcriptase inhibitor, from chromene 4 is provided, where the intermediate was subjected to a chlorotitanium-mediated aldol reaction with acetaldehyde to selectively produce (±)-8a.