Joachim Denner

TL;DR: Viral proteins were shown to be expressed in primary melanomas, metastases, and melanoma cell lines by immunohistochemistry, immunofluorescence, and Western blot analyses using specific antisera and for the first time, antibodies against HERV-K were found in melanoma patients.

TL;DR: The first clinical trial of (alginate‐encapsulated) porcine islet cell transplantation in New Zealand, which was approved by the New Zealand Government as an open‐label phase I/IIa safety/efficacy trial, offers the possibility to analyze microbiological safety in a prospective clinical study.

TL;DR: Evaluating the feasibility and safety of a hybrid liver support system with extracorporeal plasma separation and bioreactor perfusion in patients with acute liver failure who had already fulfilled the criteria for high urgency liver transplantation (LTx) found it safe and well‐tolerated.

TL;DR: Highly sensitive and specific methods have been developed to analyze the PERV status of donor pigs and to monitor recipients for PERV infection, including selection of PERV-C-negative, low-producer pigs, generation of an effective vaccine, selection of effective antiretrovirals, and generation of animals transgenic for a PERv-specific short hairpin RNA inhibiting PERV expression by RNA interference.

TL;DR: The results indicate a much lower prevalence (or even complete absence) of XMRV in prostate tumor patients in Germany, and one possible reason for this could be a geographically restricted incidence of X MRV infections.