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Joachim von Pawel

Researcher at University of Texas MD Anderson Cancer Center

Publications -  144
Citations -  27028

Joachim von Pawel is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Lung cancer & Chemotherapy. The author has an hindex of 52, co-authored 142 publications receiving 25012 citations.

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Diagnostische Bedeutung zirkulierender DNA- Fragmente in der Onkologie. Diagnostic importance of circulating DNA fragments in oncology

TL;DR: The physiological and pathophysiological background of the arrangement of DNA as nucleosomes and of its release into circulation is shown, and the diagnostic relevance of qualitative and quantitative changes in circulating DNA for screening, differential diagnosis, prognosis, monitoring of systemic therapies, early prediction of therapy response and detection of recurrence in malignant diseases is reviewed.
Journal ArticleDOI

Treatment of advanced recurrent NSCLC with daily oral vinorelbine: A phase I trial.

TL;DR: A phase I dose finding study in which a regimen of daily oral vinorelbine was evaluated in pretreated patients with advanced NSCLC and the primary end point was the identification of the maximum tolerated dose.
Proceedings ArticleDOI

Abstract 2376: Improved progression-free survival (PFS) in patients with short tumor telomere length: Subgroup analysis from a randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced NSCLC .

TL;DR: It is suggested that imetelstat given as maintenance therapy prolongs progression-free survival (PFS) in pts with advanced NSCLC whose tumors have short telomeres as measured by qPCR, consistent with the hypothesis that clinical benefit from telomerase inhibition is greater in patients with tumors possessing shortTelomeres.