J
Joan Balog Shelton
Researcher at California Institute of Technology
Publications - 58
Citations - 3264
Joan Balog Shelton is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Fetal hemoglobin & Hemoglobin. The author has an hindex of 31, co-authored 58 publications receiving 3255 citations. Previous affiliations of Joan Balog Shelton include Georgia Regents University & University of Illinois at Chicago.
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High Performance Liquid Cbromatographic Separation of Globin Chains on a Large-Pore C4 Column
TL;DR: In this article, the resolution of human and baboon globin chains was obtained by HPLC on a Vydac large-pore C4 column using a gradient between aqueous trifluoroacetic acid (TFA) and triflooracetic acids in acetonitrile.
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Evidence for multiple structural genes for the gamma chain of human fetal hemoglobin.
Walter A. Schroeder,Titus H.J. Huisman,J R Shelton,Joan Balog Shelton,E F Kleihauer,Andrée M. Dozy,B Robberson +6 more
TL;DR: The fetal hemoglobin components of 17 additional infants are examined and it is observed that position 136 of the γ chain may be occupied not only by a glycyl residue, as previously reported, but also by an alanyl residue.
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An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: application to catalase.
TL;DR: The poor cleavage of a -Met-Thr- bond in catalase by cyanogen bromide has been improved by modifying the conditions of the reaction by increasing the concentration of the reactants.
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The Amino Acid Sequence of the γ Chain of Human Fetal Hemoglobin
TL;DR: The 146 amino acid residues of the γ chain of human fetal hemoglobin have been placed in sequence and the differences between the α and γ chains are responsible for the differences in the properties of the two molecules.
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THE PRESENT STATUS OF THE HETEROGENEITY OF FETAL HEMOGLOBIN IN β‐THALASSEMIA: AN ATTEMPT TO UNIFY SOME OBSERVATIONS IN THALASSEMIA AND RELATED CONDITIONS*
Titus H.J. Huisman,Walter A. Schroeder,Georgi D. Efremov,H. Duma,B. Mladenovski,Carol B. Hyman,Eliezer A. Rachmilewitz,Nicole Bouver,A. Miller,Anne R. Brodie,J. Roger Shelton,Joan Balog Shelton,Gerald Apell +12 more
TL;DR: This work aims to demonstrate the efforts towards in-situ applicability of EMMARM, which aims to provide real-time information about the physical properties of EMTs and their applications in the treatment of cancer.