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Titus H.J. Huisman
Researcher at Georgia Regents University
Publications - 674
Citations - 17123
Titus H.J. Huisman is an academic researcher from Georgia Regents University. The author has contributed to research in topics: Hemoglobin & Thalassemia. The author has an hindex of 60, co-authored 674 publications receiving 16966 citations. Previous affiliations of Titus H.J. Huisman include United States Department of Veterans Affairs & Pennsylvania State University.
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Journal ArticleDOI
Studies on the heterogeneity of hemoglobin. IX. The use of Tris(hydroxymethyl)aminomethanehcl buffers in the anion-exchange chromatography of hemoglobins.
Titus H.J. Huisman,Andrée Dozy +1 more
TL;DR: A modified procedure for the separation of various hemoglobin types by anion exchange chromatography has been presented andDEAE-Sephadex, A-50 medium, was preferred over DEAE-cellulose as chromatographic medium.
Journal ArticleDOI
DNA sequence variation associated with elevated fetal G gamma globin production.
J.G. Gilman,Titus H.J. Huisman +1 more
TL;DR: Calculations show that T at -158 is associated with a three- to 11-fold increase in production per G gamma gene, which is an order of magnitude less than that associated with the previously identified -202 C----G substitution of high Hb F G gamma-beta+-HPFH.
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Separation of tryptic peptides of normal and abnormal a, β, γ, and δ hemoglobin chains by high-performance liquid chromatography
TL;DR: High-performance liquid chromatography was used to separate tryptic peptides of the normal a, β, γ, and δ chains of human hemoglobins A, F, and A 2 and of the abnormal chains of 25 hemoglobin variants.
Journal ArticleDOI
Evidence for multiple structural genes for the gamma chain of human fetal hemoglobin.
Walter A. Schroeder,Titus H.J. Huisman,J R Shelton,Joan Balog Shelton,E F Kleihauer,Andrée M. Dozy,B Robberson +6 more
TL;DR: The fetal hemoglobin components of 17 additional infants are examined and it is observed that position 136 of the γ chain may be occupied not only by a glycyl residue, as previously reported, but also by an alanyl residue.
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Separation of human hemoglobins by DEAE-cellulose chromatography using glycine-KCN-NaC1 developers.
TL;DR: This chromatographic procedure uses DEAE-cellulose as ion exchanger and glycine-KCN-NaC1 solutions as developers and the separation of many hemoglobins types is greatly improved.