Joan S. Hunt

TL;DR: The idea that placental HLA‐G proteins facilitate semiallogeneic pregnancy by inhibiting maternal immune responses to foreign (paternal) antigens via these actions on immune cells is now well established, and the postulate that the recombinant counterparts of these proteins may be used as powerful tools for preventing immune rejection of transplanted organs is gaining in popularity.

TL;DR: A transport model is proposed in which maternal IgG binds FcRn at low pH in endosomes within the syncytiotrophoblast, and this corresponds with the pH dependence of IgG binding to F cRn and is consistent with the presence of Fc Rn in syncyTiotrophicoblast.

TL;DR: Observations are consistent with the idea that FasL at the maternal-fetal interface protects the placenta against a maternal leukocytic influx that reduces fertility.

TL;DR: The results of this study show that TNF-alpha is synthesized by cells in both extraembryonic membranes and maternal tissues during human gestation and that transcription in specific types of cells is influenced by gestational age, consistent with a major role in the dynamic developmental events of human pregnancy.

TL;DR: The results reveal that the IRE1α-XBP-1, PERK-ATF4, and ATF6α pathways constitute novel upstream regulatory pathways of angiogenesis by modulating VEGF transcription.