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Joanne Babiarz

Researcher at Rutgers University

Publications -  11
Citations -  439

Joanne Babiarz is an academic researcher from Rutgers University. The author has contributed to research in topics: Cell adhesion molecule & Schwann cell. The author has an hindex of 10, co-authored 11 publications receiving 419 citations.

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Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development

TL;DR: The combined results indicate that Nr-CAM and L1 play a role in cerebellar granule cell development, and suggest that closely related molecules in the L1 family have overlapping functions.
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Spatiotemporal heterogeneity of CNS radial glial cells and their transition to restricted precursors.

TL;DR: It is demonstrated that spatially restricted subpopulations of radial glia along the dorsal-ventral axis acquire different markers for neuronal or glial precursors during CNS development.
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Collagen fibril assembly by corneal fibroblasts in three-dimensional collagen gel cultures: small-diameter heterotypic fibrils are deposited in the absence of keratan sulfate proteoglycan.

TL;DR: The assembly and deposition of small-diameter fibrils with a collagen composition and structure identical to that seen in the corneal stroma in the absence of proteoglycans typical of the secondary cornean stroma imply that although proteoglycan-collagen interactions may function in the establishment of interfibrillar spacing and lamellar organization, collagen-Collagen interactions are the major parameter in the regulation of fibril diameter.
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Cell adhesion and neurite outgrowth are promoted by neurofascin NF155 and inhibited by NF186

TL;DR: Analysis of Fc fusion proteins representing different extracellular regions of NF indicate that NF186 inhibits cell adhesion and neurite outgrowth, and the inhibition is associated with the region containing the mucin-like domain.
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Neurofascin interactions play a critical role in clustering sodium channels, ankyrinG and βIV spectrin at peripheral nodes of Ranvier

TL;DR: A critical early role for axonal NF in clustering of Na+ channels at nodes of Ranvier via interactions with receptors on Schwann cells is suggested by analysis of effects of NF-Fc fusion proteins in Schwann cell-DRG neuron myelinating cocultures.