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Showing papers by "Joanne E. Martin published in 1998"


Journal ArticleDOI
TL;DR: It is reported that the intensity of RET-like immunostaining of motoneurons in ALS is decreased significantly to 81% of control values, and the proportion of all large mot oneurons showing RET- like immunoreactivity in ALS remains high (82-85%) and is not significantly different to controls.

19 citations


Journal ArticleDOI
TL;DR: Mouse Genome Database (MGD), Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, Maine (URL: http://www.jax.informatics.org/).
Abstract: 12. Mouse Genome Database (MGD), Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, Maine. World Wibe Web (URL: http://www.informatics.jax.org/). (10/97). 13. Mathew S, Murty VVVS, Cheifetz S, George D, Massague J, Chaganti RSK. (1994) Genomics 20, 114-115 14. Bonyadi M, Cui W, Nagase H, Akhurst RJ. (1996) Genomics 33, 328-329 15. Imbeaud S, Faure E, Lamarre I, Mattei MG, di Clemente N, Tizard R, Carre-Eusebe D, Belville C, Tragethon L, Tonkin C, Nelson J, McAuliffe M, Bidart, J-M, Lababidi A, Josso N, Cate RL, Picard J-Y. (1995) Nat Genet 11, 382-388 16. Visser JA, McLuskey A, van Beers T, Weghuis DO, van Kessel AG, Grootegoed JA, Themmen AP. (1995) Biochem Biophys Res Commun 215, 1029-1036 17. Mishina Y, Tizard R, Deng JM, Pathak BG, Copeland NG, Jenkins NA, Cate RL, Behringer RR. (1997) Biochem Biophys Res Common 237,741-746

8 citations



Patent
09 Apr 1998
TL;DR: In this article, a method for producing a transgenomic ES cell comprising the whole or a part of a heterologous chromosome is described, which comprises the steps of tagging a chromosome or a parts of a chromosome in a cell with a dominant selectable marker, inducing microcell formation in the cell, isolating the microcells and irradiating them, fusing the microcell to ES cells, and selecting for hybrids comprising the chromosome or part of the chromosome.
Abstract: The present invention discloses a method for producing a transgenomic ES cell comprising the whole or a part of a heterologous chromosome. The method comprises the steps of: a) tagging a chromosome or a part of a chromosome in a cell with a dominant selectable marker; b) inducing microcell formation in the cell; c) isolating the microcells and irradiating them; d) fusing the microcells to ES cells; e) selecting for hybrids comprising the chromosome or part of the chromosome.

5 citations