J
Joanne M. Hilden
Researcher at Boston Children's Hospital
Publications - 109
Citations - 5496
Joanne M. Hilden is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Leukemia & Infant Acute Lymphoblastic Leukemia. The author has an hindex of 36, co-authored 107 publications receiving 4928 citations. Previous affiliations of Joanne M. Hilden include University of Minnesota & Cleveland Clinic.
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Journal ArticleDOI
A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a children's Cancer Group Study
Vassilios I. Avramis,Susan Sencer,Antonia Periclou,Harland N. Sather,Bruce Bostrom,Lewis J. Cohen,Alice G. Ettinger,Lawrence J. Ettinger,Janet Franklin,Paul S. Gaynon,Joanne M. Hilden,Beverly J. Lange,Fataneh Majlessipour,Pracad Mathew,Michael N. Needle,Joseph P. Neglia,Gregory H. Reaman,John S. Holcenberg +17 more
TL;DR: Intensive pegaspargase for newly diagnosed ALL should be tested further in a larger population, and correlation between asparaginase enzymatic activity and depletion of asparagine or glutamine in serum and cerebrospinal fluid asparagus depletion was similar with both enzyme preparations.
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Central Nervous System Atypical Teratoid/Rhabdoid Tumor: Results of Therapy in Children Enrolled in a Registry
Joanne M. Hilden,Sharon O. Meerbaum,Peter C. Burger,Jonathan L. Finlay,Anna J. Janss,Bernd W. Scheithauer,Andrew W. Walter,L B Rorke,Jaclyn A. Biegel +8 more
TL;DR: Aggressive therapy has prolonged the natural history in a subset of children and Prospective multi-institutional and national clinical trials designed specifically for AT/RT are needed.
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Parent and Physician Perspectives on Quality of Care at the End of Life in Children With Cancer
Jennifer W. Mack,Joanne M. Hilden,Jan Watterson,Caron Moore,Brian G Turner,Holcombe E. Grier,Jane C. Weeks,Joanne Wolfe +7 more
TL;DR: For parents of children who die of cancer, doctor-patient communication is the principal determinant of high-quality physician care.
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Attitudes and Practices Among Pediatric Oncologists Regarding End-of-Life Care: Results of the 1998 American Society of Clinical Oncology Survey
Joanne M. Hilden,Ezekiel J. Emanuel,Diane L. Fairclough,Michael P. Link,Kathleen M. Foley,Brian C. Clarridge,Lowell E. Schnipper,Robert J. Mayer +7 more
TL;DR: Pediatric oncologists are working to integrate symptom control, psychosocial support, and palliative care into the routine care of the seriously ill child, although barriers exist that make such comprehensive care a challenge.
Journal ArticleDOI
Analysis of prognostic factors of acute lymphoblastic leukemia in infants: report on CCG 1953 from the Children's Oncology Group.
Joanne M. Hilden,Patricia A. Dinndorf,Sharon O. Meerbaum,Harland N. Sather,Doojduen Villaluna,Nyla A. Heerema,Ron McGlennen,Franklin O. Smith,William G. Woods,Wanda L. Salzer,Helen S. Johnstone,ZoAnn E. Dreyer,Gregory H. Reaman +12 more
TL;DR: This is the first cooperative group trial characterizing all infants at the molecular level for MLL/11q23 rearrangement, and a rank order of significance for negative impact on prognosis of CD10 negativity, age younger than 6 months, and MLL rearrangements, in that order.