J
Joanne Paquin
Researcher at Université du Québec à Montréal
Publications - 36
Citations - 1008
Joanne Paquin is an academic researcher from Université du Québec à Montréal. The author has contributed to research in topics: P19 cell & Cellular differentiation. The author has an hindex of 14, co-authored 35 publications receiving 925 citations.
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Journal ArticleDOI
Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes.
TL;DR: The results suggest that the OT/OTR system plays an important role in cardiogenesis by promoting cardiomyocyte differentiation in OT- and DMSO-supplemented cultures.
Journal ArticleDOI
Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system.
Steve Poirier,Annik Prat,Edwige Marcinkiewicz,Joanne Paquin,Babykumari P Chitramuthu,David C. Baranowski,Benoît Cadieux,Hugh P.J. Bennett,Nabil G. Seidah +8 more
TL;DR: Data support a novel role for NARC‐1/PCSK9 in CNS development, distinct from that in cholesterogenic organs such as liver.
Journal ArticleDOI
Oxytocin in cardiac ontogeny
Marek Jankowski,Bogdan A. Danalache,Donghao Wang,Pangala V. Bhat,Fadi Hajjar,Mieczyslaw Marcinkiewicz,Joanne Paquin,Samuel M. McCann,Jolanta Gutkowska +8 more
TL;DR: A maximal OT and OTR protein level is shown in the developing rat heart at day 21 of gestation and postnatal days 1-4, when cardiac myocytes are at a stage of intense hyperplasia, suggesting that OT can be involved in developmental formation of the coronary vessels.
Journal ArticleDOI
Nitric Oxide Signaling in Oxytocin-Mediated Cardiomyogenesis
Bogdan A. Danalache,Bogdan A. Danalache,Joanne Paquin,Wang Donghao,Ryszard Grygorczyk,Jennifer C. Moore,Christine L. Mummery,Jolanta Gutkowska,Marek Jankowski +8 more
TL;DR: Interestingly, l‐NAME alone decreased the expression of anti‐stage specific embryonic antigen‐1 marker of the undifferentiated state and induced some beating colonies as well as GFP in P19Cl6‐GFP cells.
Journal ArticleDOI
RhoA/ROCK and Cdc42 regulate cell‐cell contact and N‐cadherin protein level during neurodetermination of P19 embryonal stem cells
TL;DR: The results indicate that the RhoA/ROCK pathway regulates cadherin protein level and cell-cell interactions during neurodetermination, with an impact on the efficiency of the process.