[신간의 별자리x] 우리/미술, 그리고 ‘슬픔의 박물관’

The growing commercial interest in indoor location-based services (ILBS) has spurred recent development of many indoor positioning techniques. Due to the absence of global positioning system (GPS) signal, many other signals have been proposed for indoor usage. Among them, Wi-Fi (802.11) emerges as a promising one due to the pervasive deployment of wireless LANs (WLANs). In particular, Wi-Fi fingerprinting has been attracting much attention recently because it does not require line-of-sight measurement of access points (APs) and achieves high applicability in complex indoor environment. This survey overviews recent advances on two major areas of Wi-Fi fingerprint localization: advanced localization techniques and efficient system deployment. Regarding advanced techniques to localize users, we present how to make use of temporal or spatial signal patterns, user collaboration, and motion sensors. Regarding efficient system deployment, we discuss recent advances on reducing offline labor-intensive survey, adapting to fingerprint changes, calibrating heterogeneous devices for signal collection, and achieving energy efficiency for smartphones. We study and compare the approaches through our deployment experiences, and discuss some future directions.

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Wi-Fi Fingerprint-Based Indoor Positioning: Recent Advances and Comparisons

Since the publication of the human reference genome, the identities of specific genes associated with human diseases are being discovered at a rapid rate. A central problem is that the biological activity of these genes is often unclear. Detailed investigations in model vertebrate organisms, typically mice, have been essential for understanding the activities of many orthologues of these disease-associated genes. Although gene-targeting approaches and phenotype analysis have led to a detailed understanding of nearly 6,000 protein-coding genes, this number falls considerably short of the more than 22,000 mouse protein-coding genes. Similarly, in zebrafish genetics, one-by-one gene studies using positional cloning, insertional mutagenesis, antisense morpholino oligonucleotides, targeted re-sequencing, and zinc finger and TAL endonucleases have made substantial contributions to our understanding of the biological activity of vertebrate genes, but again the number of genes studied falls well short of the more than 26,000 zebrafish protein-coding genes. Importantly, for both mice and zebrafish, none of these strategies are particularly suited to the rapid generation of knockouts in thousands of genes and the assessment of their biological activity. Here we describe an active project that aims to identify and phenotype the disruptive mutations in every zebrafish protein-coding gene, using a well-annotated zebrafish reference genome sequence, high-throughput sequencing and efficient chemical mutagenesis. So far we have identified potentially disruptive mutations in more than 38% of all known zebrafish protein-coding genes. We have developed a multi-allelic phenotyping scheme to efficiently assess the effects of each allele during embryogenesis and have analysed the phenotypic consequences of over 1,000 alleles. All mutant alleles and data are available to the community and our phenotyping scheme is adaptable to phenotypic analysis beyond embryogenesis.

A Systematic Genome-Wide Analysis of Zebrafish Protein-Coding Gene Function

The relevance of food composition for human health has increased consumers' interest in the consumption of fruits and vegetables, as well as foods enriched in bioactive compounds and nutraceuticals. This fact has led to a growing attention of suppliers on reuse of agro-industrial wastes rich in healthy plant ingredients. On this matter, grape has been pointed out as a rich source of bioactive compounds. Currently, up to 210 million tons of grapes (Vitis vinifera L.) are produced annually, being the 15% of the produced grapes addressed to the wine-making industry. This socio-economic activity generates a large amount of solid waste (up to 30%, w/w of the material used). Winery wastes include biodegradable solids namely stems, skins, and seeds. Bioactive compounds from winery by-products have disclosed interesting health promoting activities both in vitro and in vivo. This is a comprehensive review on the phytochemicals present in winery by-products, extraction techniques, industrial uses, and biological activities demonstrated by their bioactive compounds concerning potential for human health.

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Natural Bioactive Compounds from Winery By-Products as Health Promoters: A Review

Summary Covalent organic frameworks (COFs) are a new type of crystalline porous polymers known for chemical stability, excellent structural regularity, robust framework, and inherent porosity, making them promising materials for capturing various types of pollutants from aqueous solutions. This review thoroughly presents the recent progress and advances of COFs and COF-based materials as superior adsorbents for the efficient removal of toxic heavy metal ions, radionuclides, and organic pollutants. Information about the interaction mechanisms between various pollutants and COF-based materials are summarized from the macroscopic and microscopic standpoints, including batch experiments, theoretical calculations, and advanced spectroscopy analysis. The adsorption properties of various COF-based materials are assessed and compared with other widely used adsorbents. Several commonly used strategies to enhance COF-based materials’ adsorption performance and the relationship between structural property and sorption ability are also discussed. Finally, a summary and perspective on the opportunities and challenges of COFs and COF-based materials are proposed to provide some inspiring information on designing and fabricating COFs and COF-based materials for environmental pollution management.

Orderly Porous Covalent Organic Frameworks-based Materials: Superior Adsorbents for Pollutants Removal from Aqueous Solutions

Environmental issues are a critical factor for the today industry competitiveness. Indeed, the society and the individual consumers could set a common framework for companies’ commitment and engagement regarding environment protection. Redesign the process, recover by-products or reuse effluents are some of the possible actions towards an eco-efficient strategy. Nevertheless, a point remains crucial in such mission: the ability to defend natural ecosystems from polluted wastewaters. For such purpose, a wastewater treatment plant that maximizes removal efficiency and minimizes investment and operation costs is a key factor. Brewery and winery are traditional industries with an important economic value in the agro-food sector. In 2003, the total beer production in the European Union (18 countries) was 344 x 10 m, being recorded around 1800 breweries with 110 thousand employees. If Norway, Switzerland and Turkey are also included, those numbers rise up to 358 x 10 m, 1839 units and 117 thousand, respectively. The excise revenue from beer industry in all these countries reaches over 8800 x 10 € (The Brewers of Europe, 2004). The worldwide wine production is 261 x 10 m (data from 2002), of which 69 % from Europe, 18 % from America, 5 % from Asia, 4 % from Africa and 4 % from Oceania. The worldwide wine consumption (2002) is 228 x 10 m, distributed by Europe (68 %), America (20 %), Asia (7 %), Africa (3 %) and Oceania (2 %) (OIV, 2002). This chapter intends to present some key points on design and operation in wastewater treatment of brewery and winery industries. Therefore, an introduction of the industrial processes is first presented and then wastewater characteristics and treatment processes are discussed. Finally, the experience of a collaborative effort between

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Brewery and winery wastewater treatment : some focal points of design and operation

https://repositorium.sdum.uminho.pt/bitstream/1822/42964/1/document_38940_1.pdf

Resources recovery in the dairy industry: bioelectricity production using a continuous microbial fuel cell

Maintaining consistent radio maps for WiFi fingerprinting-based indoor positioning systems is an essential step to improve the performance of the positioning engines. The radio maps consist of WiFi fingerprints collected at a predefined set of positions/places within a positioning area. Each fingerprint consists of the identification and radio signal level of the surrounding Access Points (APs). Due to the wide proliferation of WiFi networks, it is very common to observe 10 to 20 APs at a single position and more than 50 APs across a single building. However, in practical, not all of the detected APs are useful for the position estimation process. Some of them might have weak signals at certain positions or might have less significance for a position's fingerprint. Thus, those useless APs will add additional computational overheads during the position estimation, and consequently they will reduce the overall performance of the positioning engines. A similar phenomenon also occurs with some of the collected fingerprints. While it is widely accepted that the larger and more detailed the radio map is, the better is the accuracy of the positioning system, we found that some of the fingerprint samples on the radio maps do not contribute significantly to the estimation process. In this paper, we propose two methods for filtering the positioning radio maps: APs filtering and Fingerprints filtering. Then we report on the results of a set of experiments that have been done to evaluate the performance of a WiFipositioning radio map before and after applying the filtering approaches. The results show that there is possibility to simplify the radio maps of the positioning engines without significant degradation on the positioning precision and accuracy, and therefore to reduce the processing time for estimating the position of a tracked WiFi tag. This result has an important impact on increasing the number of tags a single instance of a WiFi positioning engine can handle at a time.

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Removing useless APs and fingerprints from WiFi indoor positioning radio maps

Photo-luminescent carbon dots (CD) have become promising nanomaterials and their synthesis from natural products has attracted attention by the possibility of making the most of affordable, sustainable and, readily-available carbon sources. Here, we report on the synthesis, characterization and bioimaging potential of CDs produced from diverse extensively produced fruits: kiwi, avocado and pear. The in vitro cytotoxicity and anticancer potential of those CDs were assessed by comparing human epithelial cells from normal adult kidney and colorectal adenocarcinoma cells. In vivo toxicity was evaluated using zebrafish embryos given their peculiar embryogenesis, with transparent embryos developing ex-utero, allowing a real-time analysis. In vitro and in vivo experiments revealed that the synthesized CD presented toxicity only at concentrations of ≥1.5 mg mL-1. Kiwi CD exhibited the highest toxicity to both cells lines and zebrafish embryos, presenting lower LD50 values. Interestingly, despite inducing lower cytotoxicity in normal cells than the other CDs, black pepper CDs resulted in higher toxicity in vivo. The bio-distribution of CD in zebrafish embryos upon uptake was investigated using fluorescence microscopy. We observed a higher accumulation of CD in the eye and yolk sac, avocado CD being the ones more retained, indicating their potential usefulness in bio-imaging applications. This study shows the action of fruit-based CDs from kiwi, avocado and pear. However the compounds present in these fruit-based CDs and their mechanism of action as a bioimaging agent need to be further explored.

Biocompatibility and Bioimaging Potential of Fruit-Based Carbon Dots.

https://repositorium.sdum.uminho.pt/bitstream/1822/47120/1/document_47018_1.pdf

João Peixoto

Papers

Brewery and winery wastewater treatment : some focal points of design and operation

Resources recovery in the dairy industry: bioelectricity production using a continuous microbial fuel cell

Removing useless APs and fingerprints from WiFi indoor positioning radio maps

Biocompatibility and Bioimaging Potential of Fruit-Based Carbon Dots.

Adsorption of marine phycotoxin okadaic acid on a covalent organic framework