J
Joel Simrén
Researcher at University of Gothenburg
Publications - 41
Citations - 819
Joel Simrén is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 19 publications receiving 136 citations. Previous affiliations of Joel Simrén include Sahlgrenska University Hospital.
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Journal ArticleDOI
The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease.
Joel Simrén,Antoine Leuzy,Thomas K. Karikari,Abdul Hye,Andrea Lessa Benedet,Juan Lantero-Rodriguez,Niklas Mattsson-Carlgren,Michael Schöll,Michael Schöll,Patrizia Mecocci,Bruno Vellas,Magda Tsolaki,Iwona Kłoszewska,Hilkka Soininen,Simon Lovestone,Dag Aarsland,Dag Aarsland,Oskar Hansson,Pedro Rosa-Neto,Eric Westman,Kaj Blennow,Kaj Blennow,Henrik Zetterberg,Nicholas J. Ashton,Nicholas J. Ashton +24 more
TL;DR: In this paper, the diagnostic and disease-monitoring potential of plasma biomarkers in mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia and cognitively unimpaired (CU) individuals was investigated.
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Diagnostic and prognostic value of serum NfL and p-Tau181 in frontotemporal lobar degeneration
Alberto Benussi,Thomas K. Karikari,Nicholas J. Ashton,Stefano Gazzina,Enrico Premi,Luisa Benussi,Roberta Ghidoni,Juan Lantero Rodriguez,Andreja Emeršič,Joel Simrén,Giuliano Binetti,Silvia Fostinelli,Marcello Giunta,Roberto Gasparotti,Henrik Zetterberg,Kaj Blennow,Barbara Borroni +16 more
TL;DR: The assessment of serum NfL and p-Tau181 may provide a comprehensive view of FTLD, aiding in the differential diagnosis, in staging disease severity and in defining survival probability.
Journal ArticleDOI
Neurochemical signs of astrocytic and neuronal injury in acute COVID-19 normalizes during long-term follow-up.
Nelly Kanberg,Nelly Kanberg,Joel Simrén,Arvid Edén,Arvid Edén,Lars-Magnus Andersson,Lars-Magnus Andersson,Staffan Nilsson,Nicholas J. Ashton,Pär-Daniel Sundvall,Bengt Nellgård,Kaj Blennow,Kaj Blennow,Henrik Zetterberg,Magnus Gisslén,Magnus Gisslén +15 more
TL;DR: In this article, the authors investigated whether plasma biomarkers of CNS injury were associated with neurologic sequelae after coronavirus disease 2019 (COVID-19) and found no correlation between persistent neurological symptoms and CNS injury biomarkers in the acute phase.
Journal ArticleDOI
An update on fluid biomarkers for neurodegenerative diseases: recent success and challenges ahead.
TL;DR: Common diseases such as dementia with Lewy bodies, Parkinson's disease and frontotemporal dementias, are still without reliable diagnostic biomarkers, although emerging techniques show promising pilot results for some of these diseases.
Journal ArticleDOI
Plasma biomarkers for Alzheimer’s Disease in relation to neuropathology and cognitive change
Denis S. Smirnov,Nicholas J. Ashton,Kaj Blennow,Henrik Zetterberg,Joel Simrén,Juan Lantero-Rodriguez,Thomas K. Karikari,Annie Hiniker,Robert A. Rissman,David P. Salmon,Douglas Galasko +10 more
TL;DR: In this paper , a series of 312 well-characterized longitudinally followed research subjects with plasma available within 5 years or less before autopsy and examined these biomarkers in relation to a spectrum of AD and related pathologies.