J
Joerg Huelsken
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 69
Citations - 11179
Joerg Huelsken is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Stem cell & Wnt signaling pathway. The author has an hindex of 36, co-authored 63 publications receiving 9715 citations. Previous affiliations of Joerg Huelsken include ISREC & University of Seville.
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Journal ArticleDOI
Niche-Mediated Integrin Signaling Supports Steady-State Hematopoiesis in the Spleen.
Shubham Haribhau Mehatre,Irene Mariam Roy,Atreyi Biswas,Devila Prit,Sarah Schouteden,Joerg Huelsken,Catherine M. Verfaillie,Satish Khurana +7 more
TL;DR: In this paper, the role of POSTN-ITGAV axis in lymphohematopoietic activity in spleen that hosts a rare population of HSCs, the functional regulation of which is not clearly known.
Journal ArticleDOI
Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes.
Vasilis S. Dionellis,Maxim Norkin,Angeliki Karamichali,Giacomo G. Rossetti,Joerg Huelsken,Paloma Ordóñez-Morán,Thanos D. Halazonetis +6 more
TL;DR: In this article, the authors examined colorectal tumours that developed in mice with Apclox/lox, LSL-KrasG12D, and Tp53lox/ lox targetable alleles.
Journal ArticleDOI
424. Successful Immunotherapy of Cancer Stem Cells Requires Memory and the Adaptive Immune System of the Host
TL;DR: This poster presents a probabilistic reconstruction of the response of the immune system to EPFL-conf-212635 to high-energy radiolysis and shows clear patterns in response to the proton-proton collisions.
Posted ContentDOI
Niche mediated integrin signaling supports steady state hematopoiesis in spleen
Shubham Haribhau Mehatre,Irene Mariam Roy,Atreyi Biswas,Devila Prit,Sarah Schouteden,Joerg Huelsken,Catherine M. Verfaillie,Satish Khurana +7 more
TL;DR: Overall, it is demonstrated that POSTN-ITGAV interaction plays important role in spleen lympho-hematopoiesis.
Journal ArticleDOI
Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinoma
George M. Ramzy,Maxim Norkin,Thibaud Koessler,Lionel Voirol,M Tihy,Dina Hany,Thomas Alexander Mckee,Frédéric Ris,Nicolas C. Buchs,Mylène Docquier,Christian Toso,Laura Rubbia-Brandt,Gaetan Bakalli,Stéphane Guerrier,Joerg Huelsken,Patrycja Nowak-Sliwinska +15 more
TL;DR: In this article , the authors proposed a new approach for designing personalized treatment for colorectal cancer patients, by combining ex vivo organoid efficacy testing with mathematical modeling of the results.