J
Johanna Loomba
Researcher at University of Virginia
Publications - 31
Citations - 1134
Johanna Loomba is an academic researcher from University of Virginia. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 8 publications receiving 747 citations.
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Journal ArticleDOI
A Pilot Study of Focused Ultrasound Thalamotomy for Essential Tremor
W. Jeffrey Elias,Diane S. Huss,Tiffini Voss,Johanna Loomba,Mohamad Khaled,Eyal Zadicario,Robert C. Frysinger,Scott A. Sperling,Scott A. Wylie,Stephen J. Monteith,Jason Druzgal,Binit B. Shah,Madaline B. Harrison,Max Wintermark +13 more
TL;DR: In this pilot study, essential tremor improved in 15 patients treated with MRI-guided focused ultrasound thalamotomy, and large, randomized, controlled trials will be required to assess the procedure's efficacy and safety.
Journal ArticleDOI
Imaging Findings in MR Imaging–Guided Focused Ultrasound Treatment for Patients with Essential Tremor
Max Wintermark,Jason Druzgal,Diane S. Huss,Mohamad Khaled,Stephen J. Monteith,Prashant Raghavan,T. Huerta,L.C. Schweickert,B. Burkholder,Johanna Loomba,Eyal Zadicario,Y. Qiao,Binit B. Shah,John Snell,Matt Eames,Robert C. Frysinger,Neal F. Kassell,W. J. Elias +17 more
TL;DR: MR imaging–guided focused sonography can accurately ablate a precisely delineated target, with typical imaging findings seen in the days, weeks, and months following the treatment.
Journal ArticleDOI
IL-13 is a driver of COVID-19 severity.
Alexandra N. Donlan,Tara E. Sutherland,Chelsea Marie,Saskia Preissner,Benjamin T. Bradley,Rebecca M Carpenter,Jeffrey M. Sturek,Jennie Z. Ma,G. Brett Moreau,Jeffrey R. Donowitz,Gregory A. Buck,Myrna G. Serrano,Stacey L. Burgess,Mayuresh M. Abhyankar,Cameron Mura,Philip E. Bourne,Robert Preissner,Mary K. Young,Genevieve Lyons,Johanna Loomba,Sarah J. Ratcliffe,Melinda D. Poulter,Amy J. Mathers,Anthony J. Day,Anthony J. Day,Barbara J. Mann,Judith E. Allen,Judith E. Allen,William A. Petri +28 more
TL;DR: In this article, the authors reported that IL-13 levels were associated with the need for mechanical ventilation in 2 independent patient cohorts and that patients who acquired COVID-19 while prescribed Dupilumab, a mAb that blocks IL-3 and IL-4 signaling, had less severe disease.
Posted ContentDOI
IL-13 Predicts the Need for Mechanical Ventilation in COVID-19 Patients
Alexandra N. Donlan,Tara E. Sutherland,Chelsea Marie,Saskia Preissner,Ben T Bradley,Rebecca M Carpenter,Jeffrey M. Sturek,Jennie Z. Ma,Brett Moreau,Jeffrey R. Donowitz,Jeffrey R. Donowitz,Gregory A. Buck,Myrna G. Serrano,Stacey L. Burgess,Mayuresh M. Abhyankar,Cameron Mura,Philip E. Bourne,Robert Preissner,Mary Young,Genevieve Lyons,Johanna Loomba,Sarah J. Ratcliffe,Melinda D. Poulter,Amy J. Mathers,Anthony J. Day,Anthony J. Day,Barbara J. Mann,Judith E. Allen,Judith E. Allen,William A. Petri +29 more
TL;DR: Hierarchical clustering, Kaplan-Meier curves, and odds ratios demonstrated that two cytokines, IL-13 and IL-7 and bFGF were predictive for intubation in COVID-19 positive patients.
Journal ArticleDOI
Safety and pharmacokinetics of sodium nitrite in patients with subarachnoid hemorrhage: a Phase IIA study
Edward H. Oldfield,Johanna Loomba,Stephen J. Monteith,R. Webster Crowley,Ricky Medel,Daryl R. Gress,Neal F. Kassell,Aaron S. Dumont,Craig Sherman +8 more
TL;DR: Results of the current study suggest that safe and potentially therapeutic levels of nitrite can be achieved and sustained in critically ill patients after SAH from a ruptured cerebral aneurysm.