J
Johannes Beck
Researcher at University of Basel
Publications - 78
Citations - 3620
Johannes Beck is an academic researcher from University of Basel. The author has contributed to research in topics: Aerobic exercise & Randomized controlled trial. The author has an hindex of 23, co-authored 73 publications receiving 3075 citations. Previous affiliations of Johannes Beck include University of Zurich & University Hospital of Basel.
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Journal ArticleDOI
The link between sleep, stress and BDNF
Anne Eckert,S. Karen,Johannes Beck,Serge Brand,Ulrich Hemmeter,Martin Hatzinger,Edith Holsboer-Trachsler +6 more
TL;DR: The hypothesis that chronic stress might induce a deregulation of the HPA system leading in the long term to sleep disturbance and decreased BDNF levels is proposed, whereas acute sleep deprivation, can be used as therapeutical intervention in some insomniac or depressed patients as compensatory process to normalizeBDNF levels.
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Unfavorable polysomnographic sleep patterns predict poor sleep and poor psychological functioning 3 years later in patients with restless legs syndrome.
TL;DR: In patients with RLS, irrespective of medication or duration of treatment, poor objective sleep patterns at diagnosis predicted both poor psychological functioning and poor sleep about 3 years after diagnosis, suggesting the need for more thorough medical and psychotherapeutic treatment and monitoring.
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Repeated Cortisol Awakening Response as Predictor of Antidepressant Treatment Outcome with Duloxetine.
TL;DR: Repeated testing of the cortisol awakening response during early treatment is a putative predictive marker of antidepressant treatment outcome with duloxetine, and patients with a higher decrease in saliva cortisol measures between baseline and 10 days of treatment show a higher decreases in HDRS-21 scores.
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Dexamethasone stimulated gene expression in peripheral blood indicates glucocorticoid-receptor hypersensitivity in job-related exhaustion
Andreas Menke,Janine Arloth,Markus Gerber,Monika Rex-Haffner,Manfred Uhr,Florian Holsboer,Elisabeth B. Binder,Edith Holsboer-Trachsler,Johannes Beck +8 more
TL;DR: In this article, the authors used the Maslach Burnout Inventory (MBI) and Shirom-Melamed Burnout Measure (SMBM) to assess the severity of job-related exhaustion and found increased basal cortisol levels and an enhanced suppression of plasma cortisol concentrations following dexamethasone.
Journal ArticleDOI
Akt2 Gene is Associated with Anxiety and Neuroticism in Humans
Lucia Engeli,Marcel Delahaye,Stefan Borgwardt,Jürgen Gallinat,Daniel J. Müller,Marc Walter,Undine E. Lang,Johannes Beck +7 more
TL;DR: A connection between different genotypes of the Akt2 gene and personality traits concerning anxiety and depression may be of importance for the understanding of the pathophysiology of depressive and anxiety disorders.