J
Johannes S. de Jong
Researcher at Utrecht University
Publications - 12
Citations - 2426
Johannes S. de Jong is an academic researcher from Utrecht University. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 10, co-authored 12 publications receiving 2169 citations. Previous affiliations of Johannes S. de Jong include University of Groningen & University Medical Center Groningen.
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Journal ArticleDOI
Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results
Gooitzen M. van Dam,George Themelis,Lucia M. A. Crane,Niels J. Harlaar,Niels J. Harlaar,Rick G. Pleijhuis,W. Kelder,Athanasios Sarantopoulos,Johannes S. de Jong,Henriette J. G. Arts,Ate G.J. van der Zee,Joost Bart,Philip S. Low,Vasilis Ntziachristos +13 more
TL;DR: In patients with ovarian cancer, intraoperative tumor-specific fluorescence imaging with an FR-α–targeted fluorescent agent showcased the potential applications in patients with Ovarian cancer for improved intraoperative staging and more radical cytoreductive surgery.
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Obtaining adequate surgical margins in breast-conserving therapy for patients with early-stage breast cancer: current modalities and future directions.
Rick G. Pleijhuis,Maurits Graafland,Jakob de Vries,Joost Bart,Johannes S. de Jong,Gooitzen M. van Dam +5 more
TL;DR: This review presents the status of pre- and intraoperative modalities currently used in BCT and innovative intraoperative approaches, such as positron emission tomography, radioguided occult lesion localization, and near-infrared fluorescence optical imaging, are addressed, which have to prove their potential value in improving surgical outcome and reducing the need for re-excision in B CT.
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Tumor-specific uptake of fluorescent bevacizumab-IRDye800CW microdosing in patients with primary breast cancer: a phase I feasibility study
Laetitia E. Lamberts,Maximillian Koch,Johannes S. de Jong,Arthur Adams,Jürgen Glatz,Mariëtte E.G. Kranendonk,Anton G.T. Terwisscha van Scheltinga,Liesbeth Jansen,Jakob de Vries,Marjolijn N. Lub-de Hooge,Carolien P. Schröder,Annelies Jorritsma-Smit,Matthijs D. Linssen,Esther de Boer,Bert van der Vegt,Wouter B. Nagengast,Sjoerd G. Elias,Sabrina Oliveira,Arjen J. Witkamp,Willem P.Th.M. Mali,Elsken van der Wall,Paul J. van Diest,Elisabeth G.E. de Vries,Vasilis Ntziachristos,Gooitzen M. van Dam +24 more
TL;DR: This study shows that systemic administration of the bevacizumab–IRDye800CW tracer is safe for breast cancer guidance and confirms tumor and tumor margin uptake as evaluated by a systematic validation methodology.
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Intraoperative assessment of biliary anatomy for prevention of bile duct injury: a review of current and future patient safety interventions
K. Tim Buddingh,Vincent B. Nieuwenhuijs,Lianne van Buuren,Jan B F Hulscher,Johannes S. de Jong,Gooitzen M. van Dam +5 more
TL;DR: The critical-view-of-safety approach should be used during laparoscopic cholecystectomy, and hyperspectral cholangiography and near-infrared fluorescence cholangsiography are promising novel techniques to prevent BDI and thus increase patient safety.
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Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: a single-centre feasibility study
Niels J. Harlaar,Marjory Koller,Steven J de Jongh,Barbara L. van Leeuwen,Patrick H. J. Hemmer,Schelto Kruijff,Robert J. van Ginkel,Lukas B. Been,Johannes S. de Jong,Gursah Kats-Ugurlu,Matthijs D. Linssen,Annelies Jorritsma-Smit,Marleen van Oosten,Wouter B. Nagengast,Vasilis Ntziachristos,Gooitzen M. van Dam +15 more
TL;DR: Molecular fluorescence-guided surgery using the near-infrared fluorescent tracer bevacizumab-IRDye800CW is safe and feasible and might be of added value for the treatment of patients with colorectal peritoneal metastases through improved patient selection and optimisation of cytoreductive surgery.