V
Vincent B. Nieuwenhuijs
Researcher at University Medical Center Groningen
Publications - 130
Citations - 8874
Vincent B. Nieuwenhuijs is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Pancreatitis & Acute pancreatitis. The author has an hindex of 35, co-authored 118 publications receiving 7062 citations. Previous affiliations of Vincent B. Nieuwenhuijs include Flinders University & VU University Amsterdam.
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Journal ArticleDOI
A step-up approach or open necrosectomy for necrotizing pancreatitis
Hjalmar C. van Santvoort,Marc G. Besselink,Olaf J. Bakker,H. Sijbrand Hofker,Marja A. Boermeester,Cornelis H. C. Dejong,Harry van Goor,A. F. Schaapherder,Casper H.J. van Eijck,Thomas L. Bollen,Bert van Ramshorst,Vincent B. Nieuwenhuijs,Robin Timmer,Johan S. Laméris,Philip M Kruyt,Eric R. Manusama,Erwin van der Harst,George P. van der Schelling,Tom M. Karsten,Eric J. Hesselink,Cornelis J. H. M. van Laarhoven,Camiel Rosman,Koop Bosscha,Ralph J. de Wit,Alexander P. Houdijk,Maarten S. van Leeuwen,Erik Buskens,Hein G. Gooszen,Hein G. Gooszen,Abstr Act +29 more
TL;DR: A minimally invasive step-up approach, as compared with open necrosectomy, reduced the rate of the composite end point of major complications or death among patients with necrotizing pancreatitis and infected necrotic tissue.
Journal ArticleDOI
Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial
Marc G. Besselink,Hjalmar C. van Santvoort,Erik Buskens,Erik Buskens,Marja A. Boermeester,Harry van Goor,Harro M. Timmerman,Vincent B. Nieuwenhuijs,Thomas L. Bollen,Bert van Ramshorst,Ben J.M. Witteman,Camiel Rosman,Rutger J. Ploeg,Menno A. Brink,Alexander F. Schaapherder,Cornelis H. C. Dejong,Peter J. Wahab,Cees J. H. M. van Laarhoven,Erwin van der Harst,Casper H.J. van Eijck,Miguel A. Cuesta,Louis M. A. Akkermans,Hein G. Gooszen +22 more
TL;DR: In patients with predicted severe acute pancreatitis, probiotic prophylaxis with this combination of probiotic strains did not reduce the risk of infectious complications and was associated with an increased risk of mortality.
Journal Article
Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial. Commentary
Juhani Sand,Isto Nordback,Marc G. Besselink,Hjalmar C. van Santvoort,Erik Buskens,Marja A. Boermeester,Harry van Goor,Harro M. Timmerman,Vincent B. Nieuwenhuijs,Thomas L. Bollen,Bert van Ramshorst,Ben J.M. Witteman,Camiel Rosman,Rutger J. Ploeg,Menno A. Blink,Alexander F. Schaapherder,Cornelis H. C. Dejong,Peter J. Wahab,Ceesj H. M. Van Laarhoven,Erwin van der Harst,Casper H.J. van Eijck,Miguel A. Cuesta,Louis M. A. Akkermans,Hein G. Gooszen +23 more
TL;DR: In this article, the effects of probiotic prophylaxis in patients with predicted severe acute pancreatitis were evaluated in a multicentre randomised, double-blind, placebo-controlled trial.
Journal ArticleDOI
A conservative and minimally invasive approach to necrotizing pancreatitis improves outcome.
Hjalmar C. van Santvoort,Olaf J. Bakker,Thomas L. Bollen,Marc G. Besselink,Usama Ahmed Ali,A. Marjolein Schrijver,Marja A. Boermeester,Harry van Goor,Cornelis H. C. Dejong,Casper H.J. van Eijck,Bert van Ramshorst,Alexander F. Schaapherder,Erwin van der Harst,Sijbrand Hofker,Vincent B. Nieuwenhuijs,Menno A. Brink,Philip M Kruyt,Eric R. Manusama,George P. van der Schelling,Tom M. Karsten,Eric J. Hesselink,Cornelis J. H. M. van Laarhoven,Camiel Rosman,Koop Bosscha,Ralph J. de Wit,Alexander P. Houdijk,Miguel A. Cuesta,Peter J. Wahab,Hein G. Gooszen +28 more
TL;DR: Almost 62% of patients with necrotizing pancreatitis can be treated without an intervention and with low mortality, and in patients with infected necrosis, delayed intervention and catheter drainage as first treatment improves outcome.
Journal ArticleDOI
Endoscopic or surgical step-up approach for infected necrotising pancreatitis : A multicentre randomised trial
Sandra van Brunschot,Janneke van Grinsven,Hjalmar C. van Santvoort,Olaf J. Bakker,Marc G. Besselink,Marja A. Boermeester,Thomas L. Bollen,Koop Bosscha,Stefan A.W. Bouwense,Marco J. Bruno,Vincent C. Cappendijk,Esther C. J. Consten,Cornelis H. C. Dejong,Casper H.J. van Eijck,Willemien G. Erkelens,Harry van Goor,Wilhelmina M U van Grevenstein,Jan Willem Haveman,Sijbrand Hofker,Jeroen M. Jansen,Johan S. Laméris,Krijn P. van Lienden,Maarten Meijssen,Chris J. J. Mulder,Vincent B. Nieuwenhuijs,Jan-Werner Poley,Rutger Quispel,Rogier de Ridder,Tessa E H Römkens,Joris J. Scheepers,Nicolien J. Schepers,Matthijs P. Schwartz,Tom C.J. Seerden,B W Marcel Spanier,Jan Willem A Straathof,Marin Strijker,Robin Timmer,Niels G. Venneman,Frank P. Vleggaar,Rogier P. Voermans,Ben J.M. Witteman,Hein G. Gooszen,Marcel G. W. Dijkgraaf,Paul Fockens,Eric R. Manusama,Mohammed Hadithi,Camiel Rosman,Alexander F. Schaapherder,Erik J. Schoon +48 more
TL;DR: In patients with infected necrotising pancreatitis, the endoscopic step-up approach was not superior to the surgical step- up approach in reducing major complications or death, and the rate of pancreatic fistulas and length of hospital stay were lower in the endoscopy group.