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John A. Walker

Researcher at University of Kentucky

Publications -  17
Citations -  1149

John A. Walker is an academic researcher from University of Kentucky. The author has contributed to research in topics: Ambystoma mexicanum & Amphibian. The author has an hindex of 15, co-authored 17 publications receiving 1116 citations.

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Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration

TL;DR: Many new candidate gene sequences were discovered for the first time and these will greatly enable future studies of wound healing, epigenetics, genome stability, and nerve-dependent blastema formation and outgrowth using the axolotl model.
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Early gene expression during natural spinal cord regeneration in the salamander Ambystoma mexicanum

TL;DR: The study illustrates the utility of a salamander model for identifying genes and gene functions that may enhance regenerative ability in mammals and shows that a diverse injury response is activated in concert with extracellular matrix remodeling mechanisms during the early acute phase of natural spinal cord regeneration.
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From biomedicine to natural history research: EST resources for ambystomatid salamanders

TL;DR: This study developed ESTs for Mexican axolotl and Eastern tiger salamander, species with deep and diverse research histories, to highlight the value of developing resources in traditional model systems where the likelihood of information transfer to multiple, closely related taxa is high, thus simultaneously enabling both laboratory and natural history research.
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Origin of amphibian and avian chromosomes by fission, fusion, and retention of ancestral chromosomes

TL;DR: The maintenance of gene order relationships between chromosomal segments that have greatly expanded and contracted in salamander and chicken genomes, respectively, suggests selection to maintain synteny relationships and/or extremely low rates of chromosomal rearrangement.
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Sal-Site: Integrating new and existing ambystomatid salamander research and informational resources

TL;DR: Sal-Site was developed to integrate new and existing ambystomatid salamander research resources in support of this model system and is accessible at http://www.ambystoma.org.