John C. Cheronis

TL;DR: Elevated levels of autoantibodies to the C-terminal region of ribosomal P proteins appear to be a specific marker for SLE, and are associated with both severe depression and psychosis in this disease.

TL;DR: In this article, a method for evaluating a biological condition of a subject using a calibrated profile data set derived from a data set having a plurality of members, each member being a quantitative measure of the amount of the subject's RNA or protein as distinct constituents in a panel of constituents.

TL;DR: In this article, the authors propose a method to identify the biological condition of a subject based on a sample from the subject. But the method is not suitable for the analysis of a large set of individuals.

TL;DR: Assessment of peripheral blood gene expression in active and stable RA is associated with increased expression of circulating inflammatory markers whereas increases in inflammatory gene expression are diminished in patients with stable disease on either DMARD or anti-TNF-α therapy.

TL;DR: In this paper, a method of specifically suppressing an undesired immune response in a mammal suffering from such a response was proposed, which consisted of preparing a construct comprising at least one discrete antigenically recognizable moiety corresponding to an antigenic determinant of an antigen causing the undesired immunity response bound to a pharmacologically acceptable carrier wherein the number of moieties bound to the carrier and the spacing of the moieties on the carrier are such that the construct does not elicit an immune response to the moiety but does directly compete with the antigen for receptors on an immunocompetent