J
John Calvin Coffey
Researcher at University Hospital Limerick
Publications - 142
Citations - 4923
John Calvin Coffey is an academic researcher from University Hospital Limerick. The author has contributed to research in topics: Mesentery & Medicine. The author has an hindex of 32, co-authored 125 publications receiving 4037 citations. Previous affiliations of John Calvin Coffey include National University of Ireland, Galway & University College Cork.
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Journal ArticleDOI
Ileal pouch anal anastomosis: analysis of outcome and quality of life in 3707 patients.
Victor W. Fazio,Ravi P. Kiran,Feza H. Remzi,John Calvin Coffey,John Calvin Coffey,Helen M. Heneghan,Hasan T. Kirat,Elena Manilich,Bo Shen,Sean T. Martin +9 more
TL;DR: IPAA is an excellent option for patients with MUC, IC, FAP, and select patients with Crohn's disease and functional outcomes and QOL were good or excellent in 95% of patients and similar in each histopathological subgroup.
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Excisional surgery for cancer cure: therapy at a cost.
John Calvin Coffey,Jiang Huai Wang,Myles Smith,David Bouchier-Hayes,Thomas G. Cotter,Henry Paul Redmond +5 more
TL;DR: A novel therapeutic paradigm is proposed; that the postoperative period represents a window of opportunity during which the patient may be further protected against the oncological effects of tumour removal, and therapeutic approaches that may protect patients against any oncologically adverse effects of tumor removal.
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Desulfovibrio bacterial species are increased in ulcerative colitis.
Fiachra Rowan,Neil G. Docherty,Madeline Murphy,T. Brendan Murphy,John Calvin Coffey,P. Ronan O’Connell +5 more
TL;DR: The presence of Desulfovibrio subspecies is increased in ulcerative colitis and the data presented suggest that these bacteria represent an increased percentage of the colonic microbiome in acute ulceratives colitis.
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Spatial variation of the colonic microbiota in patients with ulcerative colitis and control volunteers
Aonghus Lavelle,Grainne Lennon,Orla O'Sullivan,Neil G. Docherty,Aine Balfe,Aoife Maguire,Hugh Mulcahy,Glen A. Doherty,D. P. O’Donoghue,John Hyland,R.P. Ross,John Calvin Coffey,Kieran Sheahan,Paul D. Cotter,Fergus Shanahan,Desmond C. Winter,P. R. O'Connell +16 more
TL;DR: This study demonstrates a conserved spatial structure to the colonic microbiota, differentiating the luminal and mucosal communities, within the context of marked interpersonal variability.
Journal ArticleDOI
The perioperative period is an underutilized window of therapeutic opportunity in patients with colorectal cancer.
Gerben J. van der Bij,Steven J. Oosterling,Robert H.J. Beelen,Sybren L. Meijer,John Calvin Coffey,Marjolein van Egmond +5 more
TL;DR: The underlying mechanisms by which surgery augments metastases outgrowth are addressed and how these insights can be used to develop perioperative therapeutic strategies for prevention of tumor recurrence are addressed.